Biotinylated Human CD19 (FMC63 scFv) CAR Detection Reagent, (CARD-LX138)

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All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

Evaluating CAR expression is an essential step in the production of CAR-T cells. Creative biolabs provides several detection reagents which are uniquely suitable for evaluation of CAR expression. Biotinylated Human CD19 (FMC63 scFv) CAR Detection Reagent, is a special detection reagent which is used to detect Human CD19 (FMC63 scFv) CAR related to the study of Acute leukemia, B-Cell lymphoma.

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Specifications

  • Target
  • CD19 (FMC63 scFv)
  • Application
  • FC, ELISA
  • Purity
  • >90%
  • Endotoxin Level
  • Less than 1.0 EU per μg by the LAL method.
  • Storage
  • For long term storage, the product should be stored at lyophilized state at -20°C or lower.
    Please protect from light and avoid repeated freeze-thaw cycles.
  • Application Notes
  • The optimal working dilutions should be determined by the end user.
  • Diseases
  • Acute leukemia, B-Cell lymphoma
  • Molecular Characterization
  • It is the biotinylated form of Monoclonal Anti-FMC63 scFv Antibody, Mouse IgG1.
  • Conjugation
  • Biotinylated
  • Size
  • 200tests
  • Expression
  • Human HEK293 cells
  • Host Species
  • Mouse
  • Species Reactivity
  • Human
  • Form
  • lyophilized

Target

  • Target Introduction
  • FMC63 is an IgG2a mouse monoclonal antibody specific for CD19, which is a target for the immunotherapy of B lineage leukaemias and lymphomas. FMC63 scFv is the most commonly used ectodomain component of CD19-specific CARs. So far, most of reported CART19 trials contain the anti-CD19 scFv derived from FMC63, including the two FDA-approved CARs Kymriah and Yescarta.
  • Target Alternative Names
  • CD19 Molecule
  • Entrez Gene ID
  • 930

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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