Creative Biolabs has a tradition of commitment. To achieve efficient execution and regulatory approval, we offer careful considerations of your program for the development of a cellular or gene therapy product – now and in the future.
EXPLORE MORE HighlightsWe focus on unmet needs and develop novel cellular and gene drugs and solutions that offer significant benefits over existing options.
EXPLORE MORE HighlightsThe advent of Chimeric Antigen Receptor T-cell (CAR-T) therapies has revolutionized the field of oncology, providing new avenues for treating various forms of cancer. Our 20 years of experience in the biotechnology sector have equipped us with the expertise and technological capabilities to support the entire lifecycle of CAR-T products, from early development to commercialization.
EXPLORE MORETo accelerate advanced breakthroughs of your projects, we offer broad range of platforms which enable our clients be free to tackle problems with cutting-edge technologies from different angles and in different methods.
EXPLORE MORE HighlightsUse the resources in our library to help you understand your options and make critical decisions for your study. We offer oncolytic virus, CAR-T, and dendritic cell related documents, as well as newsletter. If you don't find the answers you're looking for, contact us for additional assistance.
EXPLORE MORE HighlightsGet a real taste and understanding of the business and culture of one of the world's great research-based cellular and gene therapy discovery and development companies.
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Creative Biolabs has many years of experience in CARs construction for targeting Blastoma-specific antigens. We can provide highly customized and best-in-class CARs products according to our customers'special and strict requirements.
Blastoma is a kind of cancer arising in embryonic tissue, which is more commonly diagnosed in children than in adults. According to the location of cancer cells, blastoma can be further classified in to several subtypes such as Medulloblastoma, Hepatoblastoma, Nephroblastoma, Pleuropulmonary blastoma, Retinoblastoma, Neuroblastoma and Osteoblastoma. The symptoms of blastoma are variable. Radiation therapy, surgery and sometimes adjuvant chemotherapy are employed to treat this kind of diseases. However, these traditional treatments may also cause late complications and long term side effects. Adoptive cell therapy targeting specific blastoma antigens has become a very promising therapy which can overcome the disadvantages of traditional approaches. Up to now, CAR modified T-cell or NK-cell against blastoma has been applied in the clinical trials.
Depending on the most advanced techniques and experienced research team, Creative Biolabs has established an efficient and solid platform for offering customers the best service. As a famous technology services provider, Creative Biolabs has helped our customers design a series of innovative strategies according to their special requirements, which has made us garner a solid reputation globally.
Products against Blastoma-specific antigens
Please note: If you do not find your wanted antigen, please feel free to contact with us. Our highly skilled staff is very glad to help you.
| Associated malignancy | Target antigen | Receptor type | Product |
| Glioblastoma | IL13RA2 | scFv-CD28-OX40-CD3ζ | CAR-T-3-M401-2XZ |
| EGFRvIII | scFv-CD28-41BB-CD3ζ | CAR-LC056 | |
| IL13Rα2 | scFv-CD28-41BB-CD3ζ | CAR-LC236 | |
| CSPG4 | scFv-CD28-CD3ζ | CAR-MZ116 | |
| IL13Rα2 | IL13 mutein E13K-CD28-CD3ζ | CAR-MZ238 | |
| Hepatoblastoma | GPC3 | scFv-CD28-OX40-CD3ζ | CAR-T-3-L342-2XZ |
| HBV | scFv-CD28-41BB-CD3ζ | CAR-T-3-M319-2BZ | |
| ErbB2 | VHH-CD28-OX40-CD3ζ | CAR-T-3-M550-2XZ | |
| Glypican-3 (GPC3) | scFv-CD28-41BB-CD3ζ | CAR-LC180 | |
| Neuroblastoma | GD2 | scFv-CD28-41BB-CD3ζ | CAR-NK-3-M330-2BZ |
| CD171 | scFv-CD28-41BB-CD3ζ | CAR-T-3-M307-2BZ |
For any technical issues or product/service related questions, please leave your information below. Our team will contact you soon.
All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.
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