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EGFRvIII

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Epidermal growth factor receptor variant III (EGFRvIII) is an extracellular domain mutation of epidermal growth factor receptor (EGFR), which leads to a deletion of exons 2-7 of the EGFR gene and renders the mutant receptor incapable of binding any known ligand. EGFRvIII is considerably expressed in glioblastoma multiforme (GBM), which results in overexpression of the transmembrane tyrosine kinase receptor (EGFR). Therefore, EGFRvIII is related to glioblastoma multiforme (GBM).

Associated Disease
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CAT Product Name Target Species Antibody Clone Antibody Host Receptor Construction Vector Type Targeting Cell Type Inquiry & Datasheet
CAR-T-1-M315-2 Anti-EGFRvIII scFv h(CD28) CART, pCDCAR1 Human RAbDMvIII Human scFv-CD28 Lentiviral T cell   Add to Cart   Datasheet
CAR-T-1-M315-G Anti-EGFRvIII scFv h(FcεRIγ) CART, pCDCAR1 Human RAbDMvIII Human scFv-FcεRIγ Lentiviral T cell   Add to Cart   Datasheet
CAR-T-1-M315-Z Anti-EGFRvIII scFv h(CD3ζ) CART, pCDCAR1 Human RAbDMvIII Human scFv-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-T-2-M315-2G Anti-EGFRvIII scFv h(CD28-FcεRIγ) CART, pCDCAR1 Human RAbDMvIII Human scFv-CD28-FcεRIγ Lentiviral T cell   Add to Cart   Datasheet
CAR-T-2-M315-2Z Anti-EGFRvIII scFv h(CD28-CD3ζ) CART, pCDCAR1 Human RAbDMvIII Human scFv-CD28-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-T-2-M315-4G Anti-EGFRvIII scFv h(CD4-FcεRIγ) CART, pCDCAR1 Human RAbDMvIII Human scFv-CD4-FcεRIγ Lentiviral T cell   Add to Cart   Datasheet
CAR-T-2-M315-4Z Anti-EGFRvIII scFv h(CD4-CD3ζ) CART, pCDCAR1 Human RAbDMvIII Human scFv-CD4-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-T-2-M315-8Z Anti-EGFRvIII scFv h(CD8-CD3ζ) CART, pCDCAR1 Human RAbDMvIII Human scFv-CD8-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-T-2-M315-CZ Anti-EGFRvIII scFv h(b2c-CD3ζ) CART, pCDCAR1 Human RAbDMvIII Human scFv-b2c-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-T-3-M315-2BZ Anti-EGFRvIII scFv h(CD28-41BB-CD3ζ) CART, pCDCAR1 Human RAbDMvIII Human scFv-CD28-41BB-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-T-3-M315-2XZ Anti-EGFRvIII scFv h(CD28-OX40-CD3ζ) CART, pCDCAR1 Human RAbDMvIII Human scFv-CD28-OX40-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-LC055 Anti-EGFRvIII (3C10) h(41BB-CD3ζ) CAR, pCDCAR1 Human 3C10 Mouse scFv-41BB-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-LC056 Anti-EGFRvIII (3C10) h(CD28-41BB-CD3ζ) CAR, pCDCAR1 Human 3C10 Mouse scFv-CD28-41BB-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-LC057 Anti-EGFRvIII (139) h(41BB-CD3ζ) CAR, pCDCAR1 Human 139 Human scFv-41BB-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-LC221 Anti-EGFRvIII (139) h(CD28-41BB-CD3ζ) CAR, pCDCAR1 Human 139 Human scFv-CD28-41BB-CD3ζ Retroviral T cell   Add to Cart   Datasheet
CAR-LC222 Anti-EGFRvIII (139) h(CD28-CD3ζ) CAR, pCDCAR1 Human 139 Human scFv-CD28-CD3ζ Retroviral T cell   Add to Cart   Datasheet
CAR-LC242 Anti-EGFRvIII (MR1) h(-CD28-CD3ζ) CAR, pCDCAR1 Human MR1 Mouse scFv--CD28-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-LC243 Anti-EGFRvIII (MR1) h(CD28-41BB-CD3ζ) CAR, pCDCAR1 Human MR1 Mouse scFv-CD28-41BB-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-LC271 Anti-EGFRvIII (139) h(41BB-CD3ζ, FKBP/FRB) Conditional CAR, pCDCAR1 Human 139 Human scFv-FRB/FKBP-41BB-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-LC272 Anti-EGFRvIII (139) h(41BB-CD3ζ, FKBP/FRB) Conditional CAR, pCDCAR1 Human 139 Human scFv-FKBP/FRB-41BB-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-LC379 Anti-EGFRvIII h(CD28-41BB-CD3ζ, CD70) Armoured CAR, pCDCAR1 Human Human scFv-CD28-41BB-CD70-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-MZ028 Anti-EGFRvIII (RAbDMvIII) h(ICOS-CD3ζ) CAR, pCDCAR1 Human RAbDMvIII Human scFv-ICOS-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-MZ083 Anti-EGFRvIII (131) h(CD28-41BB-CD3ζ) CAR, pCDCAR1 Human 131 Human scFv-CD28-41BB-CD3ζ Retroviral T cell   Add to Cart   Datasheet
CAR-MZ085 Anti-EGFRvIII (13.1.2) h(CD28-CD3ζ) CAR, pCDCAR1 Human 13.1.2 Human scFv-CD28-CD3ζ Retroviral T cell   Add to Cart   Datasheet
CAR-MZ086 Anti-EGFRvIII (13.1.2) h(CD28-41BB-CD3ζ) CAR, pCDCAR1 Human 13.1.2 Human scFv-CD28-41BB-CD3ζ Retroviral T cell   Add to Cart   Datasheet
CAR-MZ138 Anti-EGFRvIII (MR1.1) h(DAP12) CAR, pCDCAR1 Human MR1.1 Human scFv-DAP12 Lentiviral NK cell   Add to Cart   Datasheet
CAR-MZ140 Anti-EGFRvIII (MR1.1) h(CD28-CD3ζ) CAR, pCDCAR1 Human MR1.1 Human scFv-CD28-CD3ζ Lentiviral NK cell   Add to Cart   Datasheet
CAR-YF076 Anti-EGFRvIII (CBL-YF022) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human CBL-YF022 Humanized scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-YF077 Anti-EGFRvIII (CBL-YF022) h(CD28-CD3ζ) CAR, pCDCAR1 Human CBL-YF022 Humanized scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-YF390 Anti-EGFRvIII (MR1-1) h(CD28-CD3ζ) CAR, pCDCAR1 Human MR1-1 Mouse scFv-CD28-CD3ζ Lentiviral vector T Cell   Add to Cart   Datasheet
CAR-YF429 Anti-EGFRvIII (MAb 139) h(-CD3ζ) CAR, pCDCAR1 Human MAb 139 Human scFv-CD3ζ Lentiviral vector T Cell   Add to Cart   Datasheet
CAR-YF430 Anti-EGFRvIII (MAb 139) h(CD28-CD3ζ) CAR, pCDCAR1 Human MAb 139 Human scFv-CD28-CD3ζ Lentiviral vector T Cell   Add to Cart   Datasheet
CAR-YF431 Anti-EGFRvIII (MAb 139) h(41BB-CD3ζ) CAR, pCDCAR1 Human MAb 139 Human scFv-41BB-CD3ζ Lentiviral vector T Cell   Add to Cart   Datasheet
CAR-YF432 Anti-EGFRvIII (MAb 139) h(CD28-41BB-CD3ζ) CAR, pCDCAR1 Human MAb 139 Human scFv-CD28-41BB-CD3ζ Lentiviral vector T Cell   Add to Cart   Datasheet
CAR-ZP8032 Anti-EGFRvIII (D2C7) h(CD28-CD3ζ) CAR, pCDCAR1 Human D2C7 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP8033 Anti-EGFRvIII (D2C7) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human D2C7 Mouse scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CARP-LX-036 Anti-EGFRvIII h(28ζ) CART, Combined with Kpt9274, a CAR Plus System Mouse CD28-CD3ζ Lentiviral vector   Add to Cart   Datasheet
CARP-LX-037 Anti-EGFRvIII h(28ζ) CART, Combined with Poly i:c, a CAR Plus System Mouse 806 CD28-CD3ζ Lentiviral vector   Add to Cart   Datasheet
CARP-LX-080 Anti-EGFRvIII h(BBζ) CART, Combined with Kpt9274, a CAR Plus System Mouse 41BB-CD3ζ Lentiviral vector   Add to Cart   Datasheet
CARP-LX-081 Anti-EGFRvIII h(BBζ) CART, Combined with Poly i:c, a CAR Plus System Mouse 806 41BB-CD3ζ Lentiviral vector   Add to Cart   Datasheet

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