Creative Biolabs has a tradition of commitment. To achieve efficient execution and regulatory approval, we offer careful considerations of your program for the development of a cellular or gene therapy product – now and in the future.
EXPLORE MORE HighlightsWe focus on unmet needs and develop novel cellular and gene drugs and solutions that offer significant benefits over existing options.
EXPLORE MORE HighlightsThe advent of Chimeric Antigen Receptor T-cell (CAR-T) therapies has revolutionized the field of oncology, providing new avenues for treating various forms of cancer. Our 20 years of experience in the biotechnology sector have equipped us with the expertise and technological capabilities to support the entire lifecycle of CAR-T products, from early development to commercialization.
EXPLORE MORETo accelerate advanced breakthroughs of your projects, we offer broad range of platforms which enable our clients be free to tackle problems with cutting-edge technologies from different angles and in different methods.
EXPLORE MORE HighlightsUse the resources in our library to help you understand your options and make critical decisions for your study. We offer oncolytic virus, CAR-T, and dendritic cell related documents, as well as newsletter. If you don't find the answers you're looking for, contact us for additional assistance.
EXPLORE MORE HighlightsGet a real taste and understanding of the business and culture of one of the world's great research-based cellular and gene therapy discovery and development companies.
EXPLORE MOREAll products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.
Epidermal growth factor receptor variant III (EGFRvIII) is an extracellular domain mutation of epidermal growth factor receptor (EGFR), which leads to a deletion of exons 2-7 of the EGFR gene and renders the mutant receptor incapable of binding any known ligand. EGFRvIII is considerably expressed in glioblastoma multiforme (GBM), which results in overexpression of the transmembrane tyrosine kinase receptor (EGFR). Therefore, EGFRvIII is related to glioblastoma multiforme (GBM).
Associated Disease
Loading...
| CAT | Product Name | Target Species | Antibody Clone | Antibody Host | Receptor Construction | Vector Type | Targeting Cell Type | CAR Vector Type | Inquiry & Datasheet |
| XS-1022-LX1967 | Anti-EGFRvIII (X10X491) h(CD28-41BB-CD3ζ) CAR, wild-type Sleeping Beauty vector system | Human | X10X491 | Mouse | scFv-CD28-41BB-CD3ζ | wild-type Sleeping Beauty transposon | T cell | ||
| XS-1022-LX1968 | Anti-EGFRvIII (X10X492) h(CD28-41BB-CD3ζ) CAR, wild-type Sleeping Beauty vector system | Human | X10X492 | Mouse | scFv-CD28-41BB-CD3ζ | wild-type Sleeping Beauty transposon | T cell | ||
| XS-1122-YF329 | Anti-EGFRvIII KIR CAR (scFv-KIR2DS2-DAP12, XW-329), pCDCAR1 | Human | XW-329 | Mouse | scFv-KIR2DS2 TM&ICD-2A-DAP12 | Lentiviral vector | T Cell | ||
| XS-1122-YF330 | Anti-EGFRvIII KIR CAR (scFv-KIR2DS2-DAP12, XW-330), pCDCAR1 | Human | XW-330 | Mouse | scFv-KIR2DS2 TM&ICD-2A-DAP12 | Lentiviral vector | T Cell | ||
| XS-1122-YF331 | Anti-EGFRvIII KIR CAR (scFv-KIR2DS2-DAP12, XW-331), pCDCAR1 | Human | XW-331 | Human | scFv-KIR2DS2 TM&ICD-2A-DAP12 | Lentiviral vector | T Cell | ||
| XS-1122-YF332 | Anti-EGFRvIII KIR CAR (scFv-KIR2DS2-DAP12, XW-332), pCDCAR1 | Mouse | XW-332 | Rat | scFv-KIR2DS2 TM&ICD-2A-DAP12 | Lentiviral vector | T Cell | ||
| XS-1122-YF333 | Anti-EGFRvIII KIR CAR (scFv-KIR2DS2-DAP12, XW-333), pCDCAR1 | Human | XW-333 | Humanized | scFv-KIR2DS2 TM&ICD-2A-DAP12 | Lentiviral vector | T Cell | ||
| XS-1122-YF334 | Anti-EGFRvIII KIR CAR (scFv-KIR2DS2-DAP12, XW-334), pCDCAR1 | Human | XW-334 | Humanized | scFv-KIR2DS2 TM&ICD-2A-DAP12 | Lentiviral vector | T Cell | ||
| XS-1122-YF335 | Anti-EGFRvIII KIR CAR (scFv-KIR2DS2-DAP12, XW-335), pCDCAR1 | Human | XW-335 | Mouse | scFv-KIR2DS2 TM&ICD-2A-DAP12 | Lentiviral vector | T Cell | ||
| XS-1122-YF336 | Anti-EGFRvIII KIR CAR (scFv-KIR2DS2-DAP12, XW-336), pCDCAR1 | Human | XW-336 | Mouse | scFv-KIR2DS2 TM&ICD-2A-DAP12 | Lentiviral vector | T Cell | ||
| XS-1122-YF337 | Anti-EGFRvIII KIR CAR (scFv-KIR2DS2-DAP12, XW-337), pCDCAR1 | Human | XW-337 | Humanized | scFv-KIR2DS2 TM&ICD-2A-DAP12 | Lentiviral vector | T Cell | ||
| XS-1122-YF1249 | Anti-EGFRvIII TCR-ABR (scFv-TCRα, XW-329) CAR Plasmid, pCDCAR1 | Human | XW-329 | Mouse | scFv-TCRα | Lentiviral vector | T Cell | ||
| XS-1122-YF1250 | Anti-EGFRvIII TCR-ABR (scFv-TCRα, XW-330) CAR Plasmid, pCDCAR1 | Human | XW-330 | Mouse | scFv-TCRα | Lentiviral vector | T Cell | ||
| XS-1122-YF1251 | Anti-EGFRvIII TCR-ABR (scFv-TCRα, XW-331) CAR Plasmid, pCDCAR1 | Human | XW-331 | Human | scFv-TCRα | Lentiviral vector | T Cell | ||
| XS-1122-YF1252 | Anti-EGFRvIII TCR-ABR (scFv-TCRα, XW-332) CAR Plasmid, pCDCAR1 | Mouse | XW-332 | Rat | scFv-TCRα | Lentiviral vector | T Cell | ||
| XS-1122-YF1253 | Anti-EGFRvIII TCR-ABR (scFv-TCRα, XW-333) CAR Plasmid, pCDCAR1 | Human | XW-333 | Humanized | scFv-TCRα | Lentiviral vector | T Cell | ||
| XS-1122-YF1254 | Anti-EGFRvIII TCR-ABR (scFv-TCRα, XW-334) CAR Plasmid, pCDCAR1 | Human | XW-334 | Humanized | scFv-TCRα | Lentiviral vector | T Cell | ||
| XS-1122-YF1255 | Anti-EGFRvIII TCR-ABR (scFv-TCRα, XW-335) CAR Plasmid, pCDCAR1 | Human | XW-335 | Mouse | scFv-TCRα | Lentiviral vector | T Cell | ||
| XS-1122-YF1256 | Anti-EGFRvIII TCR-ABR (scFv-TCRα, XW-336) CAR Plasmid, pCDCAR1 | Human | XW-336 | Mouse | scFv-TCRα | Lentiviral vector | T Cell | ||
| XS-1122-YF1257 | Anti-EGFRvIII TCR-ABR (scFv-TCRα, XW-337) CAR Plasmid, pCDCAR1 | Human | XW-337 | Humanized | scFv-TCRα | Lentiviral vector | T Cell | ||
| XS-0823-LX39 | Anti-hEGFRvIII (139) ICD(CD28-OX40-CD3ζ) CAR-MA, pAd5f35 Vector | Human | 139 | Adenoviral vectors |
NEWSLETTER
The latest newsletter to introduce the latest breaking information, our site updates, field and other scientific news, important events, and insights from industry leaders
LEARN MORE NEWSLETTER
NEW SOLUTION
CellRapeutics™ In Vivo Cell Engineering: One-stop in vivo T/B/NK cell and macrophage engineering services covering vectors construction to function verification.
LEARN MORE SOLUTION
NOVEL TECHNOLOGY
Silence™ CAR-T Cell: A novel platform to enhance CAR-T cell immunotherapy by combining RNAi technology to suppress genes that may impede CAR functionality.
LEARN MORE NOVEL TECHNOLOGY
NEW SOLUTION
Canine CAR-T Therapy Development: From early target discovery, CAR design and construction, cell culture, and transfection, to in vitro and in vivo function validation.
LEARN MORE SOLUTION
