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EGFRvIII

Epidermal growth factor receptor variant III (EGFRvIII) is an extracellular domain mutation of epidermal growth factor receptor (EGFR), which leads to a deletion of exons 2-7 of the EGFR gene and renders the mutant receptor incapable of binding any known ligand. EGFRvIII is considerably expressed in glioblastoma multiforme (GBM), which results in overexpression of the transmembrane tyrosine kinase receptor (EGFR). Therefore, EGFRvIII is related to glioblastoma multiforme (GBM).

Associated Disease
  • CAR Vector Products
  • CAR Viral Particles
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CAT Product Name Target SpeciesAntibody CloneAntibody HostReceptor ConstructionVector TypeTargeting Cell Type Inquiry & Datasheet
CAR-T-1-M315-2 Anti-EGFRvIII scFv h(CD28) CART, pCDCAR1 Human RAbDMvIII Human scFv-CD28 Lentiviral T cell   Add to Cart   Datasheet
CAR-T-1-M315-G Anti-EGFRvIII scFv h(FcεRIγ) CART, pCDCAR1 Human RAbDMvIII Human scFv-FcεRIγ Lentiviral T cell   Add to Cart   Datasheet
CAR-T-1-M315-Z Anti-EGFRvIII scFv h(CD3ζ) CART, pCDCAR1 Human RAbDMvIII Human scFv-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-T-2-M315-2G Anti-EGFRvIII scFv h(CD28-FcεRIγ) CART, pCDCAR1 Human RAbDMvIII Human scFv-CD28-FcεRIγ Lentiviral T cell   Add to Cart   Datasheet
CAR-T-2-M315-2Z Anti-EGFRvIII scFv h(CD28-CD3ζ) CART, pCDCAR1 Human RAbDMvIII Human scFv-CD28-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-T-2-M315-4G Anti-EGFRvIII scFv h(CD4-FcεRIγ) CART, pCDCAR1 Human RAbDMvIII Human scFv-CD4-FcεRIγ Lentiviral T cell   Add to Cart   Datasheet
CAR-T-2-M315-4Z Anti-EGFRvIII scFv h(CD4-CD3ζ) CART, pCDCAR1 Human RAbDMvIII Human scFv-CD4-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-T-2-M315-8Z Anti-EGFRvIII scFv h(CD8-CD3ζ) CART, pCDCAR1 Human RAbDMvIII Human scFv-CD8-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-T-2-M315-BZ Anti-EGFRvIII scFv h(41BB-CD3ζ) CART, pCDCAR1 Human RAbDMvIII Human scFv-41BB-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-T-2-M315-CZ Anti-EGFRvIII scFv h(b2c-CD3ζ) CART, pCDCAR1 Human RAbDMvIII Human scFv-b2c-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-T-3-M315-2BZ Anti-EGFRvIII scFv h(CD28-41BB-CD3ζ) CART, pCDCAR1 Human RAbDMvIII Human scFv-CD28-41BB-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-T-3-M315-2XZ Anti-EGFRvIII scFv h(CD28-OX40-CD3ζ) CART, pCDCAR1 Human RAbDMvIII Human scFv-CD28-OX40-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-LC055 Anti-EGFRvIII (3C10) h(41BB-CD3ζ) CAR, pCDCAR1 Human 3C10 Mouse scFv-41BB-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-LC056 Anti-EGFRvIII (3C10) h(CD28-41BB-CD3ζ) CAR, pCDCAR1 Human 3C10 Mouse scFv-CD28-41BB-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-LC242 Anti-EGFRvIII (MR1) h(-CD28-CD3ζ) CAR, pCDCAR1 Human MR1 Mouse scFv--CD28-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-LC243 Anti-EGFRvIII (MR1) h(CD28-41BB-CD3ζ) CAR, pCDCAR1 Human MR1 Mouse scFv-CD28-41BB-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-LC379 Anti-EGFRvIII h(CD28-41BB-CD3ζ, CD70) Armoured CAR, pCDCAR1 Human Human scFv-CD28-41BB-CD70-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-LC221 Anti-EGFRvIII (139) h(CD28-41BB-CD3ζ) CAR, pCDCAR1 Human 139 Human scFv-CD28-41BB-CD3ζ Retroviral T cell   Add to Cart   Datasheet
CAR-LC222 Anti-EGFRvIII (139) h(CD28-CD3ζ) CAR, pCDCAR1 Human 139 Human scFv-CD28-CD3ζ Retroviral T cell   Add to Cart   Datasheet
CAR-LC271 Anti-EGFRvIII (139) h(41BB-CD3ζ, FKBP/FRB) Conditional CAR, pCDCAR1 Human 139 Human scFv-FRB/FKBP-41BB-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-LC272 Anti-EGFRvIII (139) h(41BB-CD3ζ, FKBP/FRB) Conditional CAR, pCDCAR1 Human 139 Human scFv-FKBP/FRB-41BB-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-LC057 Anti-EGFRvIII (139) h(41BB-CD3ζ) CAR, pCDCAR1 Human 139 Human scFv-41BB-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-MZ166 Anti-EGFRvIII (MR1-1) h(CD3ζ) CAR, pCDCAR1 Human MR1-1 Mouse scFv-CD3ζ Lentiviral NK cell   Add to Cart   Datasheet
CAR-MZ073 Anti-EGFRvIII (MR-1) h(CD28-OX40-CD3ζ) CAR, pCDCAR1 Human MR-1 Mouse scFv-CD28-OX40-CD3ζ Retroviral T cell   Add to Cart   Datasheet
CAR-MZ167 Anti-EGFRvIII (MR1-1) h(41BB-CD3ζ) CAR, pCDCAR1 Human MR1-1 Mouse scFv-41BB-CD3ζ Lentiviral NK cell   Add to Cart   Datasheet
CAR-MZ168 Anti-EGFRvIII/EGFR (225) h(CD3ζ) CAR, pCDCAR1 Human 225 Mouse scFv-CD3ζ Lentiviral NK cell   Add to Cart   Datasheet
CAR-MZ074 Anti-EGFRvIII (L8A4) h(CD28-CD3ζ) CAR, pCDCAR1 Human L8A4 Mouse scFv-CD28-CD3ζ Retroviral T cell   Add to Cart   Datasheet
CAR-MZ075 Anti-EGFRvIII (L8A4) h(CD28-41BB-CD3ζ) CAR, pCDCAR1 Human L8A4 Mouse scFv-CD28-41BB-CD3ζ Retroviral T cell   Add to Cart   Datasheet
CAR-MZ076 Anti-EGFRvIII (L8A4) h(41BB-CD3ζ) CAR, pCDCAR1 Human L8A4 Mouse scFv-41BB-CD3ζ Retroviral T cell   Add to Cart   Datasheet
CAR-MZ077 Anti-EGFRvIII (Y10) h(CD3ζ) CAR, pCDCAR1 Human Y10 Mouse scFv-CD3ζ Retroviral T cell   Add to Cart   Datasheet
CAR-MZ078 Anti-EGFRvIII (Y10) h(CD28-CD3ζ) CAR, pCDCAR1 Human Y10 Mouse scFv-CD28-CD3ζ Retroviral T cell   Add to Cart   Datasheet
CAR-MZ028 Anti-EGFRvIII (RAbDMvIII) h(ICOS-CD3ζ) CAR, pCDCAR1 Human RAbDMvIII Human scFv-ICOS-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-MZ066 Anti-EGFRvIII (3C10) h(CD3ζ) CAR, pCDCAR1 Human 3C10 Mouse scFv-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-MZ079 Anti-EGFRvIII (Y10) h(41BB-CD3ζ) CAR, pCDCAR1 Human Y10 Mouse scFv-41BB-CD3ζ Retroviral T cell   Add to Cart   Datasheet
CAR-MZ080 Anti-EGFRvIII (Y10) h(OX40-CD3ζ) CAR, pCDCAR1 Human Y10 Mouse scFv-OX40-CD3ζ Retroviral T cell   Add to Cart   Datasheet
CAR-MZ067 Anti-EGFRvIII (3C10) h(CD28-CD3ζ) CAR, pCDCAR1 Human 3C10 Mouse scFv-CD28-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-MZ081 Anti-EGFRvIII (131) h(CD3ζ) CAR, pCDCAR1 Human 131 Human scFv-CD3ζ Retroviral T cell   Add to Cart   Datasheet
CAR-MZ082 Anti-EGFRvIII (131) h(CD28-CD3ζ) CAR, pCDCAR1 Human 131 Human scFv-CD28-CD3ζ Retroviral T cell   Add to Cart   Datasheet
CAR-MZ068 Anti-EGFRvIII (3C10) h(OX40-CD3ζ) CAR, pCDCAR1 Human 3C10 Mouse scFv-OX40-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-MZ069 Anti-EGFRvIII (3C10) h(CD28-OX40-CD3ζ) CAR, pCDCAR1 Human 3C10 Mouse scFv-CD28-OX40-CD3ζ Lentiviral T cell   Add to Cart   Datasheet

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