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EGFRvIII

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Epidermal growth factor receptor variant III (EGFRvIII) is an extracellular domain mutation of epidermal growth factor receptor (EGFR), which leads to a deletion of exons 2-7 of the EGFR gene and renders the mutant receptor incapable of binding any known ligand. EGFRvIII is considerably expressed in glioblastoma multiforme (GBM), which results in overexpression of the transmembrane tyrosine kinase receptor (EGFR). Therefore, EGFRvIII is related to glioblastoma multiforme (GBM).

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CAT Product Name Target Species Antibody Clone Antibody Host Receptor Construction Vector Type Targeting Cell Type CAR Vector Type Inquiry & Datasheet
CAR-MV-01LX286 Anti-EGFRvIII (mab108) h(41BB-CD3ζ) CAR, pMMLV Human mab108 Mouse scFv-41BB-CD3ζ Recombinant Moloney murine leukemia virus (MMLV) retroviral vector T cell   Add to Cart   Datasheet
CAR-MV-01LX287 Anti-EGFRvIII (mab139) h(41BB-CD3ζ) CAR, pMMLV Human mab139 Mouse scFv-41BB-CD3ζ Recombinant Moloney murine leukemia virus (MMLV) retroviral vector T cell   Add to Cart   Datasheet
CAR-SB-02LX242 Anti-EGFRvIII (clone139) h(CD28-41BB-CD3ζ) CAR, pSBCAR1 Human clone139 Humanized scFv-CD28-41BB-CD3ζ Sleeping Beauty (SB) transposon T cell   Add to Cart   Datasheet
CAR-SB-02LX280 Anti-EGFRvIII (3C10) h(CD28-OX40-CD3ζ) CAR, pSBCAR1 Human 3C10 Mouse scFv-CD28-OX40-CD3ζ Sleeping Beauty (SB) transposon T cell   Add to Cart   Datasheet
CAR-SB-02LX281 Anti-EGFRvIII (mab108) h(CD28-OX40-CD3ζ) CAR, pSBCAR1 Human mab108 Mouse scFv-CD28-OX40-CD3ζ Sleeping Beauty (SB) transposon T cell   Add to Cart   Datasheet
CAR-SB-02LX282 Anti-EGFRvIII (mab139) h(CD28-OX40-CD3ζ) CAR, pSBCAR1 Human mab139 Mouse scFv-CD28-OX40-CD3ζ Sleeping Beauty (SB) transposon T cell   Add to Cart   Datasheet
CAR-SB-02LX484 Anti-EGFRvIII (clone139) h(CD28-OX40-CD3ζ) CAR, pSBCAR1 Human clone139 Humanized scFv-CD28-OX40-CD3ζ Sleeping Beauty (SB) transposon T cell   Add to Cart   Datasheet
CAR-SB-02LX522 Anti-EGFRvIII (3C10) h(ICOS-4-1BB-CD3ζ) CAR, pSBCAR1 Human 3C10 Mouse scFv-ICOS-4-1BB-CD3ζ Sleeping Beauty (SB) transposon T cell   Add to Cart   Datasheet
CAR-SB-02LX523 Anti-EGFRvIII (mab108) h(ICOS-4-1BB-CD3ζ) CAR, pSBCAR1 Human mab108 Mouse scFv-ICOS-4-1BB-CD3ζ Sleeping Beauty (SB) transposon T cell   Add to Cart   Datasheet
CAR-SB-02LX524 Anti-EGFRvIII (mab139) h(ICOS-4-1BB-CD3ζ) CAR, pSBCAR1 Human mab139 Mouse scFv-ICOS-4-1BB-CD3ζ Sleeping Beauty (SB) transposon T cell   Add to Cart   Datasheet
CAR-SB-02LX726 Anti-EGFRvIII (clone139) h(ICOS-4-1BB-CD3ζ) CAR, pSBCAR1 Human clone139 Humanized scFv-ICOS-4-1BB-CD3ζ Sleeping Beauty (SB) transposon T cell   Add to Cart   Datasheet
XS-0622-ZP3206 Anti-EGFRvIII h(VHH1-VHH2-CD28-CD3ζ) Biepitopic CAR, pCDCAR1 Human VHH1-VHH2-CD28-CD3ζ Lentiviral vector T Cell   Add to Cart   Datasheet
XS-0622-ZP3378 Anti-EGFRvIII h(VHH1-VHH2-4-1BB-CD3ζ) Biepitopic CAR, pCDCAR1 VHH1-VHH2-4-1BB-CD3ζ Lentiviral vector T Cell   Add to Cart   Datasheet
XS-0822-YF10075 TS-IL15 SA Anti-Human EGFRvIII scFv (XW-331) 41BB-CD3ζ CAR, pCDCAR1 Human XW-331 Human 7H-YB-IL15 SA-EF1a-scFv-41BB-CD3ζ Lentiviral vector   Add to Cart   Datasheet
XS-0822-YF10076 TS-IL15 SA Anti-Mouse EGFRvIII scFv (XW-332) 41BB-CD3ζ CAR, pCDCAR1 Mouse XW-332 Rat 7H-YB-IL15 SA-EF1a-scFv-41BB-CD3ζ Lentiviral vector   Add to Cart   Datasheet
XS-0822-YF10077 TS-IL15 SA Anti-Human EGFRvIII scFv (XW-333) 41BB-CD3ζ CAR, pCDCAR1 Human XW-333 Humanized 7H-YB-IL15 SA-EF1a-scFv-41BB-CD3ζ Lentiviral vector   Add to Cart   Datasheet
XS-0822-YF10078 TS-IL15 SA Anti-Human EGFRvIII scFv (XW-334) 41BB-CD3ζ CAR, pCDCAR1 Human XW-334 Humanized 7H-YB-IL15 SA-EF1a-scFv-41BB-CD3ζ Lentiviral vector   Add to Cart   Datasheet
XS-0822-YF10482 TS-IL15 SA Anti-Human EGFRvIII scFv (XW-329) CD28-41BB-CD3ζ CAR, pCDCAR1 Human XW-329 Mouse 7H-YB-IL15 SA-EF1a-scFv-CD28-41BB-CD3ζ Lentiviral vector   Add to Cart   Datasheet
XS-0822-YF10483 TS-IL15 SA Anti-Human EGFRvIII scFv (XW-330) CD28-41BB-CD3ζ CAR, pCDCAR1 Human XW-330 Mouse 7H-YB-IL15 SA-EF1a-scFv-CD28-41BB-CD3ζ Lentiviral vector   Add to Cart   Datasheet
XS-0822-YF10484 TS-IL15 SA Anti-Human EGFRvIII scFv (XW-331) CD28-41BB-CD3ζ CAR, pCDCAR1 Human XW-331 Human 7H-YB-IL15 SA-EF1a-scFv-CD28-41BB-CD3ζ Lentiviral vector   Add to Cart   Datasheet
XS-0823-LX39 Anti-hEGFRvIII (139) ICD(CD28-OX40-CD3ζ) CAR-MA, pAd5f35 Vector Human 139 Adenoviral vectors   Add to Cart   Datasheet
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