EGFRvIII

Epidermal growth factor receptor variant III (EGFRvIII) is an extracellular domain mutation of epidermal growth factor receptor (EGFR), which leads to a deletion of exons 2-7 of the EGFR gene and renders the mutant receptor incapable of binding any known ligand. EGFRvIII is considerably expressed in glioblastoma multiforme (GBM), which results in overexpression of the transmembrane tyrosine kinase receptor (EGFR). Therefore, EGFRvIII is related to glioblastoma multiforme (GBM).

Associated Disease

CAR Vector Products Product list:

Catalog Targeting
Cell Type
Generation Antibody
Clone
Vector
Length
Vector
Type
Vector Design Antibody
Host
Data
sheet
Price
CAR-LC055 T cell Second 3C10 ~8kb Lentiviral scFv-41BB-CD3ζ Mouse Inquiry
CAR-LC056 T cell Third 3C10 ~8kb Lentiviral scFv-CD28-41BB-CD3ζ Mouse Inquiry
CAR-LC057 T cell Second 139 ~8kb Lentiviral scFv-41BB-CD3ζ Human Inquiry
CAR-LC221 T cell Third 139 ~8kb Retroviral scFv-CD28-41BB-CD3ζ Human Inquiry
CAR-LC222 T cell Second 139 ~8kb Retroviral scFv-CD28-CD3ζ Human Inquiry
CAR-LC242 T cell Second MR1 ~8kb Lentiviral scFv--CD28-CD3ζ Mouse Inquiry
CAR-LC243 T cell Third MR1 ~8kb Lentiviral scFv-CD28-41BB-CD3ζ Mouse Inquiry
CAR-LC271 T cell Second 139 ~8kb Lentiviral scFv-FRB/FKBP-41BB-CD3ζ Human Inquiry
CAR-LC272 T cell Second 139 ~8kb Lentiviral scFv-FKBP/FRB-41BB-CD3ζ Human Inquiry
CAR-LC379 T cell ~8kb Lentiviral scFv-CD28-41BB-CD70-CD3ζ Human Inquiry
CAR-MZ028 T cell Second RAbDMvIII ~8kb Lentiviral scFv-ICOS-CD3ζ Human Inquiry
CAR-MZ066 T cell First 3C10 ~8kb Lentiviral scFv-CD3ζ Mouse Inquiry
CAR-MZ067 T cell Second 3C10 ~8kb Lentiviral scFv-CD28-CD3ζ Mouse Inquiry
CAR-MZ068 T cell Second 3C10 ~8kb Lentiviral scFv-OX40-CD3ζ Mouse Inquiry
CAR-MZ069 T cell Third 3C10 ~8kb Lentiviral scFv-CD28-OX40-CD3ζ Mouse Inquiry
CAR-MZ070 T cell First MR-1 ~8kb Retroviral scFv-CD3ζ Mouse Inquiry
CAR-MZ073 T cell Third MR-1 ~8kb Retroviral scFv-CD28-OX40-CD3ζ Mouse Inquiry
CAR-MZ074 T cell Second L8A4 ~8kb Retroviral scFv-CD28-CD3ζ Mouse Inquiry
CAR-MZ075 T cell Third L8A4 ~8kb Retroviral scFv-CD28-41BB-CD3ζ Mouse Inquiry
CAR-MZ076 T cell Second L8A4 ~8kb Retroviral scFv-41BB-CD3ζ Mouse Inquiry
CAR-MZ077 T cell First Y10 ~8kb Retroviral scFv-CD3ζ Mouse Inquiry
CAR-MZ078 T cell Second Y10 ~8kb Retroviral scFv-CD28-CD3ζ Mouse Inquiry
CAR-MZ079 T cell Second Y10 ~8kb Retroviral scFv-41BB-CD3ζ Mouse Inquiry
CAR-MZ080 T cell Second Y10 ~8kb Retroviral scFv-OX40-CD3ζ Mouse Inquiry
CAR-MZ081 T cell First 131 ~8kb Retroviral scFv-CD3ζ Human Inquiry
CAR-MZ082 T cell Second 131 ~8kb Retroviral scFv-CD28-CD3ζ Human Inquiry
CAR-MZ083 T cell Third 131 ~8kb Retroviral scFv-CD28-41BB-CD3ζ Human Inquiry
CAR-MZ085 T cell Second 13.1.2 ~8kb Retroviral scFv-CD28-CD3ζ Human Inquiry
CAR-MZ086 T cell Third 13.1.2 ~8kb Retroviral scFv-CD28-41BB-CD3ζ Human Inquiry
CAR-MZ138 NK cell First MR1.1 ~8kb Lentiviral scFv-DAP12 Human Inquiry
CAR-MZ140 NK cell Second MR1.1 ~8kb Lentiviral scFv-CD28-CD3ζ Human Inquiry
CAR-MZ166 NK cell First MR1-1 ~8kb Lentiviral scFv-CD3ζ Mouse Inquiry
CAR-MZ167 NK cell Second MR1-1 ~8kb Lentiviral scFv-41BB-CD3ζ Mouse Inquiry
CAR-MZ168 NK cell First 225 ~8kb Lentiviral scFv-CD3ζ Mouse Inquiry
CAR-MZ169 NK cell Second 225 ~8kb Lentiviral scFv-41BB-CD3ζ Mouse Inquiry
CAR-T-1-M315-2 T cell First RAbDMvIII 8kb Lentiviral scFv-CD28 Human Inquiry
CAR-T-1-M315-G T cell First RAbDMvIII 8kb Lentiviral scFv-FcεRIγ Human Inquiry
CAR-T-1-M315-Z T cell First RAbDMvIII 8kb Lentiviral scFv-CD3ζ Human Inquiry
CAR-T-2-M315-2G T cell Second RAbDMvIII 8kb Lentiviral scFv-CD28-FcεRIγ Human Inquiry
CAR-T-2-M315-2Z T cell Second RAbDMvIII 8kb Lentiviral scFv-CD28-CD3ζ Human Inquiry
CAR-T-2-M315-4G T cell Second RAbDMvIII 8kb Lentiviral scFv-CD4-FcεRIγ Human Inquiry
CAR-T-2-M315-4Z T cell Second RAbDMvIII 8kb Lentiviral scFv-CD4-CD3ζ Human Inquiry
CAR-T-2-M315-8Z T cell Second RAbDMvIII 8kb Lentiviral scFv-CD8-CD3ζ Human Inquiry
CAR-T-2-M315-BZ T cell Second RAbDMvIII 8kb Lentiviral scFv-41BB-CD3ζ Human Inquiry
CAR-T-2-M315-CZ T cell Second RAbDMvIII 8kb Lentiviral scFv-b2c-CD3ζ Human Inquiry
CAR-T-3-M315-2BZ T cell Third RAbDMvIII 8kb Lentiviral scFv-CD28-41BB-CD3ζ Human Inquiry
CAR-T-3-M315-2XZ T cell Third RAbDMvIII 8kb Lentiviral scFv-CD28-OX40-CD3ζ Human Inquiry

CAR Viral Particles Product list:

Catalog Antibody
Clone
Packaging
System
Generation Gene
Construct
Promotor Packaging
Cell
Titer Data
sheet
Price
VP-CAR-LC197 RAbDMvIII Lentivirus First scFv (RAbDMvIII)-CD28 CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC198 RAbDMvIII Lentivirus Second scFv (RAbDMvIII)-FcεRIγ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC199 RAbDMvIII Lentivirus First scFv (RAbDMvIII)-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC200 RAbDMvIII Lentivirus Second scFv (RAbDMvIII)-CD28-FcεRIγ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC201 RAbDMvIII Lentivirus Second scFv (RAbDMvIII)-CD28-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC202 RAbDMvIII Lentivirus Second scFv (RAbDMvIII)-CD4-FcεRIγ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC203 RAbDMvIII Lentivirus Second scFv (RAbDMvIII)-CD4-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC204 RAbDMvIII Lentivirus Second scFv (RAbDMvIII)-CD8-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC205 RAbDMvIII Lentivirus Second scFv (RAbDMvIII)-41BB-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC206 RAbDMvIII Lentivirus Second scFv (RAbDMvIII)-b2c-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC207 RAbDMvIII Lentivirus Third scFv (RAbDMvIII)-CD28-41BB-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC208 RAbDMvIII Lentivirus Third scFv (RAbDMvIII)-CD28-OX40-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC545 3C10 Lentivirus Second scFv (3C10)-41BB-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC546 3C10 Lentivirus Second scFv (3C10)-CD28-41BB-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC547 139 Lentivirus Second scFv (139)-41BB-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC696 139 Lentivirus Second scFv (139)-CD28-41BB-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC697 139 Lentivirus Second scFv (139)-CD28-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC714 MR1 Lentivirus Second scFv (MR1)--CD28-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC715 MR1 Lentivirus Second scFv (MR1)-CD28-41BB-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC752 RAbDMvIII Lentivirus Second scFv (RAbDMvIII)-ICOS-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC777 3C10 Lentivirus First scFv (3C10)-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC778 3C10 Lentivirus Second scFv (3C10)-CD28-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC779 3C10 Lentivirus Second scFv (3C10)-OX40-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC780 3C10 Lentivirus Third scFv (3C10)-CD28-OX40-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC781 MR-1 Lentivirus First scFv (MR-1)-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC782 MR-1 Lentivirus Third scFv (MR-1)-CD28-OX40-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC783 L8A4 Lentivirus Second scFv (L8A4)-CD28-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC784 L8A4 Lentivirus Third scFv (L8A4)-CD28-41BB-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC785 L8A4 Lentivirus Second scFv (L8A4)-41BB-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC786 Y10 Lentivirus First scFv (Y10)-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC787 Y10 Lentivirus Second scFv (Y10)-CD28-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC788 Y10 Lentivirus Second scFv (Y10)-41BB-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC789 Y10 Lentivirus Second scFv (Y10)-OX40-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC790 131 Lentivirus First scFv (131)-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC791 131 Lentivirus Second scFv (131)-CD28-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC792 131 Lentivirus Third scFv (131)-CD28-41BB-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC793 13.1.2 Lentivirus Second scFv (13.1.2)-CD28-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC794 13.1.2 Lentivirus Third scFv (13.1.2)-CD28-41BB-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC835 MR1.1 Lentivirus First scFv (MR1.1)-DAP12 CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC836 MR1.1 Lentivirus First scFv (MR1.1)-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC837 MR1.1 Lentivirus Second scFv (MR1.1)-CD28-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC860 MR1-1 Lentivirus First scFv (MR1-1)-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC861 MR1-1 Lentivirus Second scFv (MR1-1)-41BB-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC862 225 Lentivirus First scFv (225)-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC863 225 Lentivirus Second scFv (225)-41BB-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
CONTACT US

USA
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Tel: 1-631-871-5806
Fax: 1-631-207-8356
Email:

Europe
Ringstrasse 4, 64401 Gross-Bieberau, Germany
Tel: 44-207-097-1828

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