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CellRapeutics™ CD19+ B Cells from Crohn's Disease Donor (XS-0426-XU2)

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All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

This product features purified CD19+ B lymphocytes harvested from donors with confirmed Crohn's disease. These cells are specifically processed to preserve their unique surface marker expressions and cytokine profiles, providing an essential tool for investigating mucosal immune dysregulation and the B cell-mediated inflammatory cascades within the gastrointestinal tract.

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Donor Information

  • Product Name
  • CellRapeutics™ CD19+ B Cells from Crohn's Disease Donor
  • Cat. No.
  • XS-0426-XU2
  • Donor Age
  • Young Adult
  • Donor Health
  • Clinically diagnosed with active or remitting Crohn's Disease. Donors exhibit chronic intestinal inflammatory profiles and are screened for relevant clinical markers associated with inflammatory bowel disease.
  • Ethnicity
  • Diverse backgrounds available, predominantly Caucasian.
  • Anticoagulant
  • Acid Citrate Dextrose, selected to counteract potential pro-thrombotic inflammatory cytokines and preserve B-cell surface receptor integrity in a high-TNFα environment.
  • Additional Donor Information
  • Each lot features CD19+ B cells from donors with clinically confirmed Crohn's Disease. Profiles include disease location, current inflammatory status, and detailed medication history, including biologics and immunosuppressants, to support studies on mucosal immunity.
  • Clinical Profile
  • Disease activity index, disease location, current medication status, and history of surgical interventions.

Additional Information

  • Medication History
  • Available upon request. Includes documentation of treatment with aminosalicylates, corticosteroids, and significant exposure to biologics or conventional immunosuppressants.
  • Formulation
  • Cryopreserved in specialized freezing medium
  • Cell Purity
  • >90%
  • Cell Viability
  • >90%
  • Mycoplasma Testing
  • Negative
  • Sterility Testing
  • Negative
  • Genetic Stability Testing
  • The donor cells maintain their native genetic profile, exhibiting no karyotypic abnormalities or chromosomal instabilities typically associated with prolonged ex vivo expansion.
  • Application
  • Drug Discovery, Immuno-oncology Research
  • Research Use Only
  • RUO
  • Quality Control
  • Each product batch undergoes rigorous testing for purity, viability, and microbial contamination.
  • Storage
  • Upon arrival, immediately transfer the vial to the liquid nitrogen.
  • Shiping
  • Dry Ice
  • Handling Notes
  • Upon thawing, it is recommended to rapidly thaw the cells in a 37°C water bath, followed by the slow addition of pre-warmed culture medium to minimize osmotic shock.
  • Warnings
  • Treat as potentially biohazardous human-derived material and handle strictly under BSL-2 guidelines using appropriate personal protective equipment.
  • Size
  • 1E7 cells/vial, 2.5E7 cells/vial
  • Keywords
  • CellRapeutics™ CD19+ B Cells from Crohn's Disease Donor, CD19+ B Cells, Crohn's Disease

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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