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CellRapeutics™ Leukopak from Cutaneous Lupus Erythematosus Donor (XS-0426-XU278)

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All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

Sourced from donors with Cutaneous Lupus Erythematosus, this product consists of a high-yield collection of PBMCs primed by skin-specific autoimmune triggers. The cell population is enriched with plasmacytoid dendritic cells and T-cell subsets that express skin-homing markers. This Leukopak is specifically curated for research into the type I interferon signature and the mechanisms of lymphocyte-mediated keratinocyte injury in localized autoimmune dermatoses.

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Donor Information

  • Product Name
  • CellRapeutics™ Leukopak from Cutaneous Lupus Erythematosus Donor
  • Cat. No.
  • XS-0426-XU278
  • Donor Age
  • Young Adult, Middle-Aged
  • Donor Health
  • Diagnosed with Cutaneous Lupus. The leukocyte population reflects a photosensitive autoimmune state, featuring skin-homing lymphocyte expansion and systemic signatures of type I interferon pathway activation.
  • Ethnicity
  • Diverse backgrounds available, predominantly African American and Hispanic cohorts.
  • Anticoagulant
  • Acid Citrate Dextrose, prioritized to preserve the skin-tropic T cell subsets and UV-sensitive immune signatures.
  • Additional Donor Information
  • Each lot features a Leukopak from donors with skin-manifested lupus. Profiles focus on skin lesion activity and systemic involvement exclusion, facilitating research on skin-homing lymphocyte subsets.
  • Clinical Profile
  • Specific subtype, biopsy confirmation, severity index score, and presence or absence of systemic involvement.

Additional Information

  • Medication History
  • Available upon request. Records of topical agents, antimalarials, and systemic immunomodulatory medications.
  • Formulation
  • Cryopreserved or Fresh options available.
  • Cell Purity
  • >90%
  • Cell Viability
  • >90%
  • Mycoplasma Testing
  • Negative
  • Sterility Testing
  • Negative
  • Genetic Stability Testing
  • The donor cells maintain their native genetic profile, exhibiting no karyotypic abnormalities or chromosomal instabilities typically associated with prolonged ex vivo expansion.
  • Application
  • Drug Discovery, Immuno-oncology Research
  • Research Use Only
  • RUO
  • Quality Control
  • Each product batch is strictly validated for high cellular viability, specific immune cell counts, and pathogen-free safety, ensuring consistent clinical phenotypes and ethical compliance for advanced immunological research.
  • Storage
  • Store fresh Leukopaks at 2°C to 8°C for immediate use, cryopreserved samples must be kept in liquid nitrogen vapor phase below -150°C.
  • Shiping
  • Dry Ice
  • Handling Notes
  • Process fresh cells within 48 hours or perform rapid thawing of cryovials in a 37°C water bath followed by gradual dilution to maximize recovery.
  • Warnings
  • Treat as potentially biohazardous human-derived material and handle strictly under BSL-2 guidelines using appropriate personal protective equipment.
  • Size
  • Full Bag, Half Bag
  • Keywords
  • CellRapeutics™ Leukopak from Cutaneous Lupus Erythematosus Donor, Leukopak, Cutaneous Lupus Erythematosus

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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