The vector of anti-FITC chimeric antigen receptor (CAR) is universal CAR constructed for the engineering of T cell to target FITC. The T cells are genetically modified through transduction with a retroviral vector expressing scFv of anti-FITC antibody linked to CD137 (4-1BB) and CD3ζ signaling domains. And the vector product was designed for the treatment of various cancers of which the cancer cells are stained with specific FITC-labeled ligand.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
|CAR-T-1-L340-G||Anti-FITC scFv h(FcεRIγ) CART, pCDCAR1|
|CAR-T-3-L340-2XZ||Anti-FITC scFv h(CD28-OX40-CD3ζ) CART, pCDCAR1|
|CAR-T-3-L340-2BZ||Anti-FITC scFv h(CD28-41BB-CD3ζ) CART, pCDCAR1|
|CAR-T-2-L340-2G||Anti-FITC scFv h(CD28-FcεRIγ) CART, pCDCAR1|
|VP-CAR-LC511||Lenti-α-FITC CAR (scFv-CD28-41BB-CD3ζ) Viral Particle|
|VP-CAR-LC249||Lenti-FITC CAR (scFv-CD28-CD3ζ, 67A4) Viral Particle|
|VP-CAR-LC248||Lenti-FITC CAR (scFv-CD28-FcεRIγ, 67A4) Viral Particle|
|VP-CAR-LC253||Lenti-FITC CAR (scFv-41BB-CD3ζ, 67A4) Viral Particle|
|VP-CAR-LC245||Lenti-FITC CAR (scFv-CD28, 67A4) Viral Particle|
|VP-CAR-LC247||Lenti-FITC CAR (scFv-CD3ζ, 67A4) Viral Particle|
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