Human B7-H3 CAR Detection Reagent, His Tag (PE) (XS-0423-LX88)

Datasheet

All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

Human B7-H3 CAR Detection Reagent, His Tag (PE) is applied for evaluating Human B7H3 CAR expression, and is suitable for FC application.

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Specifications

Target
B7-H3

Organism
Human

Application
Used for evaluating CAR expression

Purity
>90%

Endotoxin Level
Less than 1.0 EU per μg by the LAL method.

Storage
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please protect from light and avoid repeated freeze-thaw cycles.

Shelf-Life
Stable as supplied until expiry date on label.

Application Notes
The optimal working dilutions should be determined by the end user.

Diseases
autoimmune diseases

Molecular Characterization
It contains AA Gly 27 - Thr 461 (Accession # Q5ZPR3-2).

Conjugation
PE

Size
25ug

Formulation
Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization.

Expression
HEK293 cell

Host Species
Human

Species Reactivity
Human

Form
lyophilized

Target

Target Introduction
B7 homolog 3 (B7-H3), a member of the immunoglobulin superfamily, is also known CD276, which contains two Ig-like C2-type (immunoglobulin-like) domains and two Ig-like V-type (immunoglobulin-like) domains. B7-H3 may participate in the regulation of T-cell-mediated immune response. B7-H3 also plays a protective role in tumor cells by inhibiting natural-killer mediated cell lysis as well as a role of marker for detection of neuroblastoma cells. Furthermore, B7-H3 is involved in the development of acute and chronic transplant rejection and in the regulation of lymphocytic activity at mucosal surfaces. It could also play a key role in providing the placenta and fetus with a suitable immunological environment throughout pregnancy.

Target Alternative Names
B7 homolog 3

UniProt ID
Q5ZPR3-1

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

Human B7-H3 CAR Detection Reagent, His Tag (PE) (XS-0423-LX88)

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Specifications

Target

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