Human LILRB4 CAR Detection Reagent, His Tag (Biotinylated) (XS-0423-LX75)

Datasheet

All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

Human LILRB4 CAR Detection Reagent, His Tag (Biotinylated) is applied for evaluating Human LILRB4 CAR expression, and is suitable for FC application.

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Specifications

Target
LILRB4

Organism
Human

Application
Used for evaluating CAR expression

Purity
>90%

Endotoxin Level
Less than 1.0 EU per μg by the LAL method.

Storage
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please protect from light and avoid repeated freeze-thaw cycles.

Shelf-Life
Stable as supplied until expiry date on label.

Application Notes
The optimal working dilutions should be determined by the end user.

Molecular Characterization
The CAR detection reagent contains AA Gln 22 - Glu 259 of Human LILRB4.

Conjugation
Biotinylated

Size
25 tests; 100 tests

Formulation
Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization.

Expression
HEK293 cell

Host Species
Human

Species Reactivity
Human

Form
Lyophilized

Target

Target Introduction
This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. The receptor can also function in antigen capture and presentation. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity.

Target Alternative Names
leukocyte immunoglobulin like receptor B4

Entrez Gene ID
11006

UniProt ID
Q02846-1

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

Human LILRB4 CAR Detection Reagent, His Tag (Biotinylated) (XS-0423-LX75)

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Specifications

Target

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