Anti-NS3 T cell receptor, pCDTCR1(TCR-L271)

The vector of anti-NS3 T cell receptor (TCR) is constructed for the engineering of T cell to target HCV NS3. The T cells are genetically modified through transduction with a lentiviral vector expressing NS3-specific T cell receptor. And the vector product was designed for the treatment of HCV infection.


Details


Target
NS3
Target Species
HCV
Epitope
aa 1406-1415
Format
Non-modified
HLA
HLA-A2
Targeting Diseases
HCV infection
Vector Name
pCDTCR1
Vector Length
~8kb
Vector Type
Lentiviral
Antibody Host
Human

Target


Gene Name
Nonstructural protein 3
Official Symbol
NS3
Synonyms
Nonstructural protein 3; NS3; p-70
Introduction
Nonstructural protein 3 (NS3), also known as p-70, is a viral nonstructural protein that is 70 kDa cleavage product of the hepatitis C virus polyprotein. It acts as a serine protease.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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45-1 Ramsey Road, Shirley, NY 11967, USA
Tel: 1-631-871-5806
Fax: 1-631-207-8356
Email:

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