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Anti-SpeC T cell receptor, pCDTCR1(TCR-C237Z)

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The vector of anti-SpeC T cell receptor (TCR) is constructed for the engineering of T cell to target Streptococcus pyogenes SpeC. The T cells are genetically modified through transduction with a lentiviral vector expressing SpeC-specific T cell receptor. And the vector product was designed for the treatment of Streptococcal toxic shock-like disease and rheumatic fever.

Details

Target
SpeC
Target Species
Streptococcus pyogenes
Format
Single-chain
HLA
HLA-DR2a
Targeting Diseases
Streptococcal toxic shock-like disease and rheumatic fever
Vector Name
pCDTCR1
Vector Length
~8kb
Vector Type
Lentiviral
Antibody Host
Human

Target

Gene Name
SpeC
Official Symbol
SpeC
UniProt ID
Q8NKX2
Synonyms
Exotoxin type C; spyM18_0778; SpeC
Introduction
Causative agent of the symptoms associated with scarlet fever, have been associated with streptococcal toxic shock-like disease and may play a role in the early events of rheumatic fever.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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CONTACT US
45-1 Ramsey Road, Shirley, NY 11967, USA
USA: 1-631-381-2994
Europe: 44-207-097-1828
Fax: 1-631-207-8356
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CONTACT US

USA
45-1 Ramsey Road, Shirley, NY 11967, USA
Tel: 1-631-381-2994
Fax: 1-631-207-8356
Email:

Europe
Ringstrasse 4, 64401 Gross-Bieberau, Germany
Tel: 44-207-097-1828

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