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Anti-Squalene synthase T cell receptor (121), pCDTCR1 (TCR-C238Z)

The vector of anti-Squalene synthase T cell receptor (TCR) is constructed for the engineering of T cell to target Squalene synthase. The T cells are genetically modified through transduction with a lentiviral vector expressing Squalene synthase-specific T cell receptor.

Details

  • Target
  • Squalene synthase
  • Epitope
  • HIPDVITY
  • Format
  • Non-modified
  • HLA
  • HLA-B*3501
  • Vector Name
  • pCDTCR1
  • Vector Length
  • ~8kb
  • Vector Type
  • Lentiviral
  • Antibody Clone
  • 121
  • Antibody Host
  • Human

Target

  • Gene Name
  • farnesyl-diphosphate farnesyltransferase 1
  • Official Symbol
  • FDFT1
  • Synonyms
  • SS; SQS; DGPT; ERG9; FDFT1
  • Introduction
  • This gene encodes a membrane-associated enzyme located at a branch point in the mevalonate pathway. The encoded protein is the first specific enzyme in cholesterol biosynthesis, catalyzing the dimerization of two molecules of farnesyl diphosphate in a two-step reaction to form squalene.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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