Anti-TPI T cell receptor (E8), pCDTCR1 (TCR-C252Z)

The vector of anti-TPI T cell receptor (TCR) is constructed for the engineering of T cell to target Human TPI. The T cells are genetically modified through transduction with a lentiviral vector expressing TPI-specific T cell receptor. And the vector product was designed for the treatment of Melanoma.


  • Target
  • TPI
  • Target Species
  • Human
  • Epitope
  • aa 23-37
  • Format
  • Non-modified
  • HLA
  • HLA-DR1
  • Targeting Diseases
  • Melanoma
  • Vector Name
  • pCDTCR1
  • Vector Length
  • ~8kb
  • Vector Type
  • Lentiviral
  • Antibody Clone
  • E8
  • Antibody Host
  • Human


  • Gene Name
  • triosephosphate isomerase 1
  • Official Symbol
  • TPI1
  • Synonyms
  • TPI1; TIM; TPI; TPID; HEL-S-49
  • Introduction
  • This gene encodes an enzyme, consisting of two identical proteins, which catalyzes the isomerization of glyceraldehydes 3-phosphate (G3P) and dihydroxy-acetone phosphate (DHAP) in glycolysis and gluconeogenesis. Mutations in this gene are associated with triosephosphate isomerase deficiency. Pseudogenes have been identified on chromosomes 1, 4, 6 and 7. Alternative splicing results in multiple transcript variants.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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