Anti-DNA polymerase T cell receptor (Hy.2E11), pCDTCR1(TCR-C040Z)

The vector of anti-DNA polymerase T cell receptor (TCR) is constructed for the engineering of T cell to target EBV DNA polymerase. The T cells are genetically modified through transduction with a lentiviral vector expressing DNA polymerase-specific T cell receptor. And the vector product was designed for the treatment of EBV infection.


Details


Target
DNA polymerase
Target Species
EBV
Epitope
TGGVYHFVKKHVHES
Format
Murinized
HLA
HLA-DRB5*0101
Targeting Diseases
EBV infection
Vector Name
pCDTCR1
Vector Length
~8kb
Vector Type
Lentiviral
Antibody Clone
Hy.2E11
Antibody Host
Murinized

Target


Gene Name
DNA polymerase
Official Symbol
BALF5
Gene ID
UniProt ID
Synonyms
BALF5; DNA polymerase; EBV; HHV-4
Introduction
Replicates viral genomic DNA in the late phase of lytic infection, producing long concatemeric DNA. The replication complex is composed of six viral proteins: the DNA polymerase, processivity factor, primase, primase-associated factor, helicase, and ssDNA-binding protein.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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CONTACT US

USA
45-1 Ramsey Road, Shirley, NY 11967, USA
Tel: 1-631-871-5806
Fax: 1-631-207-8356
Email:

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Tel: 44-207-048-3343

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