Anti-STEAP1 T cell receptor (P2A5), pCDTCR1(TCR-C241Z)

The vector of anti-STEAP1 T cell receptor (TCR) is constructed for the engineering of T cell to target Human STEAP1. The T cells are genetically modified through transduction with a lentiviral vector expressing STEAP1-specific T cell receptor. And the vector product was designed for the treatment of Ewing sarcoma.


Details


Target
STEAP1
Target Species
Human
Epitope
YLPGVIAAI
Format
Codon-optimized and murinized
HLA
HLA-A*0201
Targeting Diseases
Ewing sarcoma
Vector Name
pCDTCR1
Vector Length
~8kb
Vector Type
Lentiviral
Antibody Clone
P2A5
Antibody Host
Murinized

Target


Gene Name
STEAP family member 1
Official Symbol
STEAP1
Gene ID
UniProt ID
Synonyms
STEAP; PRSS24
Introduction
This gene is predominantly expressed in prostate tissue, and is found to be upregulated in multiple cancer cell lines. The gene product is predicted to be a six-transmembrane protein, and was shown to be a cell surface antigen significantly expressed at cell-cell junctions.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

Related Products


Sarcoma Kits for CARs/TCRs Development 

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CONTACT US
45-1 Ramsey Road, Shirley, NY 11967, USA
USA: 1-631-381-2994
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CONTACT US

USA
45-1 Ramsey Road, Shirley, NY 11967, USA
Tel: 1-631-381-2994
Fax: 1-631-207-8356
Email:

Europe
Tel: 44-207-097-1828

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