The vector of anti-Bpep chimeric antigen receptor (CAR) is constructed for the engineering of T cells to target human Bpep. The T cells are genetically modified through transduction with a lentiviral vector expressing scFv of anti-Bpep antibody linked to FcεRIγ signaling domains. And the vector product was designed for the treatment of ovarian tumor.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
|CAR-T-1-M402-Z||Bpep h(CD3ζ) CAR, [T]|
|CAR-T-1-M402-2||Bpep h(CD28) CAR, [T]|
|CAR-T-2-M402-2G||Bpep h(CD28-FcεRIγ) CAR, [T]|
|CAR-T-3-M402-2XZ||Bpep h(CD28-OX40-CD3ζ) CAR, [T]|
|CAR-T-2-M402-8Z||Bpep h(CD8-CD3ζ) CAR, [T]|
|CAR-T-3-M402-2BZ||Bpep h(CD28-41BB-CD3ζ) CAR, [T]|
|CAR-T-2-M402-BZ||Bpep h(41BB-CD3ζ) CAR, [T]|
|CAR-T-2-M402-2Z||Bpep h(CD28-CD3ζ) CAR, [T]|
|CAR-T-2-M402-4G||Bpep h(CD4-FcεRIγ) CAR, [T]|
|CAR-T-2-M402-CZ||Bpep h(b2c-CD3ζ) CAR, [T]|
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