The vector of anti-FITC chimeric antigen receptor (CAR) is constructed for the engineering of T cells to target human FITC. The T cells are genetically modified through transduction with a lentiviral vector expressing scFv of anti-FITC antibody linked to CD3-zeta and CD137 (4-1BB) signaling domains. And the vector product was designed for targeting and killing tumors via tumor-associated antigens.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
|VP-CAR-LC254||Lenti-FITC CAR (scFv-b2c-CD3ζ, 67A4) Viral Particle|
|VP-CAR-LC511||Lenti-α-FITC CAR (scFv-CD28-41BB-CD3ζ) Viral Particle|
|CAR-T-2-L340-4Z||Anti-FITC scFv h(CD4-CD3ζ) CART, pCDCAR1|
|VP-CAR-LC252||Lenti-FITC CAR (scFv-CD8-CD3ζ, 67A4) Viral Particle|
|CAR-T-2-L340-8Z||Anti-FITC scFv h(CD8-CD3ζ) CART, pCDCAR1|
|VP-CAR-LC246||Lenti-FITC CAR (scFv-FcεRIγ, 67A4) Viral Particle|
|VP-CAR-LC247||Lenti-FITC CAR (scFv-CD3ζ, 67A4) Viral Particle|
|VP-CAR-LC248||Lenti-FITC CAR (scFv-CD28-FcεRIγ, 67A4) Viral Particle|
|CAR-T-2-L340-4G||Anti-FITC scFv h(CD4-FcεRIγ) CART, pCDCAR1|
|CAR-T-3-L340-2XZ||Anti-FITC scFv h(CD28-OX40-CD3ζ) CART, pCDCAR1|
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