The vector of anti-GD3 chimeric antigen receptor (CAR) is constructed for the engineering of T cells to target human GD3. The T cells are genetically modified through transduction with a lentiviral vector expressing scFv of anti-GD3 antibody linked to FcεRIγ signaling domains. And the vector product was designed for the treatment of GD3+ melanoma .
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
|VP-CAR-LC270||Lenti-GD3 CAR (scFv-FcεRIγ, MB3.6) Viral Particle|
|VP-CAR-LC276||Lenti-GD3 CAR (scFv-CD8-CD3ζ, MB3.6) Viral Particle|
|VP-CAR-LC280||Lenti-GD3 CAR (scFv-CD28-OX40-CD3ζ, MB3.6) Viral Particle|
|VP-CAR-LC279||Lenti-GD3 CAR (scFv-CD28-41BB-CD3ζ, MB3.6) Viral Particle|
|VP-CAR-LC275||Lenti-GD3 CAR (scFv-CD4-CD3ζ, MB3.6) Viral Particle|
|CAR-T-1-M317-2||Anti-GD3 scFv h(CD28) CART, pCDCAR1|
|VP-CAR-LC278||Lenti-GD3 CAR (scFv-b2c-CD3ζ, MB3.6) Viral Particle|
|CAR-T-2-M317-2G||Anti-GD3 scFv h(CD28-FcεRIγ) CART, pCDCAR1|
|VP-CAR-LC274||Lenti-GD3 CAR (scFv-CD4-FcεRIγ, MB3.6) Viral Particle|
|CAR-T-2-M317-8Z||Anti-GD3 scFv h(CD8-CD3ζ) CART, pCDCAR1|
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