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ABCA4

All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

In the visual cycle, acts as an inward-directed retinoid flipase, retinoid substrates imported by ABCA4 from the extracellular or intradiscal (rod) membrane surfaces to the cytoplasmic membrane surface are all-trans-retinaldehyde (ATR) and N-retinyl-phosphatidyl-ethanolamine (NR-PE). Once transported to the cytoplasmic surface, ATR is reduced to vitamin A by trans-retinol dehydrogenase (tRDH) and then transferred to the retinal pigment epithelium (RPE) where it is converted to 11-cis-retinal. The protein may play a role in photoresponse, removing ATR/NR-PE from the extracellular photoreceptor surfaces during bleach recovery.
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CAT Product Name Target Species Antibody Clone Antibody Host Receptor Construction Vector Type Targeting Cell Type CAR Vector Type Inquiry & Datasheet
CAR-CN059 Anti-ABCA4 (3F4) h(CD28-CD3ζ) CAR, pCDCAR1 Cattle 3F4 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CN060 Anti-ABCA4 (CBLNA-164) h(CD28-CD3ζ) CAR, pCDCAR1 Cattle CBLNA-164 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CN160 Anti-ABCA4 (3F4) h(41BB-CD3ζ) CAR, pCDCAR1 Cattle 3F4 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CN161 Anti-ABCA4 (CBLNA-164) h(41BB-CD3ζ) CAR, pCDCAR1 Cattle CBLNA-164 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
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