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ABI1

All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

This gene encodes a member of the Abelson-interactor family of adaptor proteins. These proteins facilitate signal transduction as components of several multiprotein complexes, and regulate actin polymerization and cytoskeletal remodeling through interactions with Abelson tyrosine kinases. The encoded protein plays a role in macropinocytosis as a component of the WAVE2 complex, and also forms a complex with EPS8 and SOS1 that mediates signal transduction from Ras to Rac. This gene may play a role in the progression of several malignancies including melanoma, colon cancer and breast cancer, and a t(10;11) chromosomal translocation involving this gene and the MLL gene has been associated with acute myeloid leukemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 14.
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CAT Product Name Target Species Antibody Clone Antibody Host Receptor Construction Vector Type Targeting Cell Type CAR Vector Type Inquiry & Datasheet
CAR-CQ0003 Anti-ABI1 (CBXS-5035) h(41BB-CD3ζ) CAR, pCDCAR1 Mouse, Rat, Human CBXS-5035 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ0004 Anti-ABI1 (CBXS-1207) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBXS-1207 Rabbit scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ3427 Anti-ABI1 (CBXS-5035) h(CD28-CD3ζ) CAR, pCDCAR1 Mouse, Rat, Human CBXS-5035 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ3428 Anti-ABI1 (CBXS-1207) h(CD28-CD3ζ) CAR, pCDCAR1 Human CBXS-1207 Rabbit scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-0320ZP43 Anti-ABI1 (DS20AB) h(CD28-CD3ζ) CAR, pCDCAR1 Human DS20AB Rabbit scFv-CD28-CD3ζ Lentiviral vector T Cell   Add to Cart   Datasheet
CAR-0320ZP44 Anti-ABI1 (DS20AB) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human DS20AB Rabbit scFv-4-1BB-CD3ζ Lentiviral vector T Cell   Add to Cart   Datasheet
CAR-0320ZP45 Anti-ABI1 (D3G6C) h(CD28-CD3ζ) CAR, pCDCAR1 Mouse D3G6C Rabbit scFv-CD28-CD3ζ Lentiviral vector T Cell   Add to Cart   Datasheet
CAR-0320ZP46 Anti-ABI1 (D3G6C) h(4-1BB-CD3ζ) CAR, pCDCAR1 Mouse D3G6C Rabbit scFv-4-1BB-CD3ζ Lentiviral vector T Cell   Add to Cart   Datasheet
CAR-0320ZP47 Anti-ABI1 (C-1) h(CD28-CD3ζ) CAR, pCDCAR1 Human C-1 Mouse scFv-CD28-CD3ζ Lentiviral vector T Cell   Add to Cart   Datasheet
CAR-0320ZP48 Anti-ABI1 (C-1) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human C-1 Mouse scFv-4-1BB-CD3ζ Lentiviral vector T Cell   Add to Cart   Datasheet
CAR-0320ZP49 Anti-ABI1 (4E2) h(CD28-CD3ζ) CAR, pCDCAR1 Human 4E2 Mouse scFv-CD28-CD3ζ Lentiviral vector T Cell   Add to Cart   Datasheet
CAR-0320ZP50 Anti-ABI1 (4E2) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human 4E2 Mouse scFv-4-1BB-CD3ζ Lentiviral vector T Cell   Add to Cart   Datasheet
CAR-0320ZP51 Anti-ABI1 (1B9) h(CD28-CD3ζ) CAR, pCDCAR1 Human 1B9 Mouse scFv-CD28-CD3ζ Lentiviral vector T Cell   Add to Cart   Datasheet
CAR-0320ZP52 Anti-ABI1 (1B9) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human 1B9 Mouse scFv-4-1BB-CD3ζ Lentiviral vector T Cell   Add to Cart   Datasheet
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