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AKAP13

All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms containing c-terminal dbl oncogene homology (DH) and pleckstrin homology (PH) domains. The DH domain is associated with guanine nucleotide exchange activation for the Rho/Rac family of small GTP binding proteins, resulting in the conversion of the inactive GTPase to the active form capable of transducing signals. The PH domain has multiple functions. Therefore, these isoforms function as scaffolding proteins to coordinate a Rho signaling pathway, function as protein kinase A-anchoring proteins and, in addition, enhance ligand-dependent activity of estrogen receptors alpha and beta.

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CAT Product Name Target Species TCR Clone Host Species Epitope Allele Vector Type Inquiry & Datasheet
TCR-YC0068 Human anti-AKAP13 T cell receptor (BA7), pCDTCR1 Human BA7 Human KLMNIQQQL HLA-A2 Lentiviral vector   Add to Cart   Datasheet
TCR-YC0069 Human anti-AKAP13 T cell receptor (BC11), pCDTCR1 Human BC11 Human KLMNIQQQL HLA-A2 Lentiviral vector   Add to Cart   Datasheet
TCR-YC0070 Human anti-AKAP13 T cell receptor (BE6), pCDTCR1 Human BE6 Human KLMNIQQQL HLA-A2 Lentiviral vector   Add to Cart   Datasheet
TCR-YC0071 Human anti-AKAP13 T cell receptor (BH1), pCDTCR1 Human BH1 Human KLMNIQQQL HLA-A2 Lentiviral vector   Add to Cart   Datasheet
TCR-YC0072 Human anti-AKAP13 T cell receptor (CB4), pCDTCR1 Human CB4 Human KLMNIQQQL HLA-A2 Lentiviral vector   Add to Cart   Datasheet
TCR-YC0073 Human anti-AKAP13 T cell receptor (H21), pCDTCR1 Human H21 Human KLMNIQQQL HLA-A2 Lentiviral vector   Add to Cart   Datasheet
TCR-YC0074 Human anti-AKAP13 T cell receptor (IH8), pCDTCR1 Human IH8 Human KLMNIQQQL HLA-A2 Lentiviral vector   Add to Cart   Datasheet
TCR-YC0075 Human anti-AKAP13 T cell receptor (J11), pCDTCR1 Human J11 Human KLMNIQQQL HLA-A2 Lentiviral vector   Add to Cart   Datasheet
TCR-YC0076 Human anti-AKAP13 T cell receptor (K2), pCDTCR1 Human K2 Human KLMNIQQQL HLA-A2 Lentiviral vector   Add to Cart   Datasheet
TCR-YC0077 Human anti-AKAP13 T cell receptor (K9), pCDTCR1 Human K9 Human KLMNIQQQL HLA-A2 Lentiviral vector   Add to Cart   Datasheet
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