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ANTXR1

All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

This gene encodes a type I transmembrane protein and is a tumor-specific endothelial marker that has been implicated in colorectal cancer. The encoded protein has been shown to also be a docking protein or receptor for Bacillus anthracis toxin, the causative agent of the disease, anthrax. The binding of the protective antigen (PA) component, of the tripartite anthrax toxin, to this receptor protein mediates delivery of toxin components to the cytosol of cells. Once inside the cell, the other two components of anthrax toxin, edema factor (EF) and lethal factor (LF) disrupt normal cellular processes. Three alternatively spliced variants that encode different protein isoforms have been described.
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CAT Product Name Target Species Antibody Clone Antibody Host Receptor Construction Vector Type Targeting Cell Type CAR Vector Type Inquiry & Datasheet
CAR-SB-02LX430 Anti-ANTXR1 (L2) h(CD28-OX40-CD3ζ) CAR, pSBCAR1 Human L2 Mouse scFv-CD28-OX40-CD3ζ Sleeping Beauty (SB) transposon T cell   Add to Cart   Datasheet
CAR-SB-02LX431 Anti-ANTXR1 (1D2) h(CD28-OX40-CD3ζ) CAR, pSBCAR1 Human 1D2 Mouse scFv-CD28-OX40-CD3ζ Sleeping Beauty (SB) transposon T cell   Add to Cart   Datasheet
CAR-SB-02LX432 Anti-ANTXR1 (T803) h(CD28-OX40-CD3ζ) CAR, pSBCAR1 Human T803 Humanized scFv-CD28-OX40-CD3ζ Sleeping Beauty (SB) transposon T cell   Add to Cart   Datasheet
CAR-SB-02LX433 Anti-ANTXR1 (M830) h(CD28-OX40-CD3ζ) CAR, pSBCAR1 Human M830 Human scFv-CD28-OX40-CD3ζ Sleeping Beauty (SB) transposon T cell   Add to Cart   Datasheet
CAR-SB-02LX434 Anti-ANTXR1 (L3) h(CD28-OX40-CD3ζ) CAR, pSBCAR1 Human L3 Human scFv-CD28-OX40-CD3ζ Sleeping Beauty (SB) transposon T cell   Add to Cart   Datasheet
CAR-SB-02LX435 Anti-ANTXR1 (L1) h(CD28-OX40-CD3ζ) CAR, pSBCAR1 Human L1 Human scFv-CD28-OX40-CD3ζ Sleeping Beauty (SB) transposon T cell   Add to Cart   Datasheet
CAR-SB-02LX672 Anti-ANTXR1 (L2) h(ICOS-4-1BB-CD3ζ) CAR, pSBCAR1 Human L2 Mouse scFv-ICOS-4-1BB-CD3ζ Sleeping Beauty (SB) transposon T cell   Add to Cart   Datasheet
CAR-SB-02LX673 Anti-ANTXR1 (1D2) h(ICOS-4-1BB-CD3ζ) CAR, pSBCAR1 Human 1D2 Mouse scFv-ICOS-4-1BB-CD3ζ Sleeping Beauty (SB) transposon T cell   Add to Cart   Datasheet
CAR-SB-02LX674 Anti-ANTXR1 (T803) h(ICOS-4-1BB-CD3ζ) CAR, pSBCAR1 Human T803 Humanized scFv-ICOS-4-1BB-CD3ζ Sleeping Beauty (SB) transposon T cell   Add to Cart   Datasheet
CAR-SB-02LX675 Anti-ANTXR1 (M830) h(ICOS-4-1BB-CD3ζ) CAR, pSBCAR1 Human M830 Human scFv-ICOS-4-1BB-CD3ζ Sleeping Beauty (SB) transposon T cell   Add to Cart   Datasheet
CAR-SB-02LX676 Anti-ANTXR1 (L3) h(ICOS-4-1BB-CD3ζ) CAR, pSBCAR1 Human L3 Human scFv-ICOS-4-1BB-CD3ζ Sleeping Beauty (SB) transposon T cell   Add to Cart   Datasheet
CAR-SB-02LX677 Anti-ANTXR1 (L1) h(ICOS-4-1BB-CD3ζ) CAR, pSBCAR1 Human L1 Human scFv-ICOS-4-1BB-CD3ζ Sleeping Beauty (SB) transposon T cell   Add to Cart   Datasheet
XS-0822-YF14 Anti-Human ANTXR1 (XW-14) h(41BB-CD3ζ) CAR IVT Plasmid, pCARIVT Human XW-14 Mouse scFv-41BB-CD3ζ In Vitro Transcription (IVT) Vector   Add to Cart   Datasheet
XS-0822-YF15 Anti-Human ANTXR1 (XW-15) h(41BB-CD3ζ) CAR IVT Plasmid, pCARIVT Human XW-15 Human scFv-41BB-CD3ζ In Vitro Transcription (IVT) Vector   Add to Cart   Datasheet
XS-0822-YF934 Anti-Human ANTXR1 (XW-14) h(CD28-CD3ζ) CAR IVT Plasmid, pCARIVT Human XW-14 Mouse scFv-CD28-CD3ζ In Vitro Transcription (IVT) Vector   Add to Cart   Datasheet
XS-0822-YF935 Anti-Human ANTXR1 (XW-15) h(CD28-CD3ζ) CAR IVT Plasmid, pCARIVT Human XW-15 Human scFv-CD28-CD3ζ In Vitro Transcription (IVT) Vector   Add to Cart   Datasheet
XS-0822-YF8594 TS-Fluc Anti-Human ANTXR1 scFv (XW-14) CD28-CD3ζ CAR, pCDCAR1 Human XW-14 Mouse 7H-YB-Fluc-EF1a-scFv-CD28-CD3ζ Lentiviral vector   Add to Cart   Datasheet
XS-0822-YF8595 TS-Fluc Anti-Human ANTXR1 scFv (XW-15) CD28-CD3ζ CAR, pCDCAR1 Human XW-15 Human 7H-YB-Fluc-EF1a-scFv-CD28-CD3ζ Lentiviral vector   Add to Cart   Datasheet
XS-0822-YF9003 TS-Fluc Anti-Human ANTXR1 scFv (XW-14) 41BB-CD3ζ CAR, pCDCAR1 Human XW-14 Mouse 7H-YB-Fluc-EF1a-scFv-41BB-CD3ζ Lentiviral vector   Add to Cart   Datasheet
XS-0822-YF9004 TS-Fluc Anti-Human ANTXR1 scFv (XW-15) 41BB-CD3ζ CAR, pCDCAR1 Human XW-15 Human 7H-YB-Fluc-EF1a-scFv-41BB-CD3ζ Lentiviral vector   Add to Cart   Datasheet
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