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APBB1

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The protein encoded by this gene is a member of the Fe65 protein family. It is an adaptor protein localized in the nucleus. It interacts with the Alzheimer's disease amyloid precursor protein (APP), transcription factor CP2/LSF/LBP1 and the low-density lipoprotein receptor-related protein. APP functions as a cytosolic anchoring site that can prevent the gene product's nuclear translocation. This encoded protein could play an important role in the pathogenesis of Alzheimer's disease. It is thought to regulate transcription. Also it is observed to block cell cycle progression by downregulating thymidylate synthase expression. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene.
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CAT Product Name Target Species Antibody Clone Antibody Host Receptor Construction Vector Type Targeting Cell Type CAR Vector Type Inquiry & Datasheet
CAR-CQ0025 Anti-APBB1 (CBXF-1179) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBXF-1179 Rabbit scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ0026 Anti-APBB1 (CBXF-1907) h(41BB-CD3ζ) CAR, pCDCAR1 Human, Mouse, Rat CBXF-1907 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ3449 Anti-APBB1 (CBXF-1179) h(CD28-CD3ζ) CAR, pCDCAR1 Human CBXF-1179 Rabbit scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ3450 Anti-APBB1 (CBXF-1907) h(CD28-CD3ζ) CAR, pCDCAR1 Human, Mouse, Rat CBXF-1907 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ6853 Anti-APBB1 (BA0242) h(CD28-CD3ζ) CAR, pCDCAR1 Human BA0242 Rabbit scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ7333 Anti-APBB1 (BA0242) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human BA0242 Rabbit scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-0320ZP215 Anti-APBB1 (DS197AB) h(CD28-CD3ζ) CAR, pCDCAR1 Human DS197AB Rabbit scFv-CD28-CD3ζ Lentiviral vector T Cell   Add to Cart   Datasheet
CAR-0320ZP216 Anti-APBB1 (DS197AB) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human DS197AB Rabbit scFv-4-1BB-CD3ζ Lentiviral vector T Cell   Add to Cart   Datasheet
CAR-0320ZP217 Anti-APBB1 (4H324) h(CD28-CD3ζ) CAR, pCDCAR1 Human 4H324 Mouse scFv-CD28-CD3ζ Lentiviral vector T Cell   Add to Cart   Datasheet
CAR-0320ZP218 Anti-APBB1 (4H324) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human 4H324 Mouse scFv-4-1BB-CD3ζ Lentiviral vector T Cell   Add to Cart   Datasheet
CAR-0320ZP220 Anti-APBB1 (CBXF-1907) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human CBXF-1907 Mouse scFv-4-1BB-CD3ζ Lentiviral vector T Cell   Add to Cart   Datasheet
CAR-0320ZP222 Anti-APBB1 (CBXF-1179) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human CBXF-1179 Rabbit scFv-4-1BB-CD3ζ Lentiviral vector T Cell   Add to Cart   Datasheet
CAR-0320ZP223 Anti-APBB1 (1F2) h(CD28-CD3ζ) CAR, pCDCAR1 Human 1F2 Mouse scFv-CD28-CD3ζ Lentiviral vector T Cell   Add to Cart   Datasheet
CAR-0320ZP224 Anti-APBB1 (1F2) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human 1F2 Mouse scFv-4-1BB-CD3ζ Lentiviral vector T Cell   Add to Cart   Datasheet
CAR-0320ZP225 Anti-APBB1 (7E7D12) h(CD28-CD3ζ) CAR, pCDCAR1 Human 7E7D12 Mouse scFv-CD28-CD3ζ Lentiviral vector T Cell   Add to Cart   Datasheet
CAR-0320ZP226 Anti-APBB1 (7E7D12) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human 7E7D12 Mouse scFv-4-1BB-CD3ζ Lentiviral vector T Cell   Add to Cart   Datasheet
CAR-0320ZP227 Anti-APBB1 (7E7A3) h(CD28-CD3ζ) CAR, pCDCAR1 Human 7E7A3 Mouse scFv-CD28-CD3ζ Lentiviral vector T Cell   Add to Cart   Datasheet
CAR-0320ZP228 Anti-APBB1 (7E7A3) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human 7E7A3 Mouse scFv-4-1BB-CD3ζ Lentiviral vector T Cell   Add to Cart   Datasheet
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