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CD20

CD20 (Cluster of Differentiation 20), also called B lymphocyte antigen CD20, is an activated-glycosylated phosphoprotein expressed on the surface of all B-cells, in human it is encoded by MS4A1 gene. CD20 plays a role in the development and differentiation of B-cells into plasma cells.its function is to enable optimal B-cell immune response, specifically against T-independent antigens.CD20 is expressed on all stages of B cell development except the first and last. It has been found that associated with B-cell lymphomas, hairy cell leukemia, B-cell chronic lymphocytic leukemia, and melanoma cancer stem cells. Therefore CD20 have been considered as a therapeutic target of monoclonal antibodies such as rituximab, obinutuzumab, Ibritumomab tiuxetan, and tositumomab, which are all active agents in the treatment of all B cell lymphomas and leukemias.

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CAT Product Name Target SpeciesAntibody CloneAntibody HostReceptor ConstructionVector TypeTargeting Cell Type Inquiry & Datasheet
CAR-NK-2-M327-CZ Anti-CD20 scFv h(b2c-CD3ζ) CARNK, pCDCAR1 Human rituximab Chimeric scFv-b2c-CD3ζ Lentiviral NK cell   Add to Cart   Datasheet
CAR-NK-3-M327-2BZ Anti-CD20 scFv h(CD28-41BB-CD3ζ) CARNK, pCDCAR1 Human rituximab Chimeric scFv-CD28-41BB-CD3ζ Lentiviral NK cell   Add to Cart   Datasheet
CAR-NK-1-M327-2 Anti-CD20 scFv h(CD28) CARNK, pCDCAR1 Human rituximab Chimeric scFv-CD28 Lentiviral NK cell   Add to Cart   Datasheet
CAR-NK-1-M327-G Anti-CD20 scFv h(FcεRIγ) CARNK, pCDCAR1 Human rituximab Chimeric scFv-FcεRIγ Lentiviral NK cell   Add to Cart   Datasheet
CAR-NK-3-M327-2XZ Anti-CD20 scFv h(CD28-OX40-CD3ζ) CARNK, pCDCAR1 Human rituximab Chimeric scFv-CD28-OX40-CD3ζ Lentiviral NK cell   Add to Cart   Datasheet
CAR-NK-1-M327-Z Anti-CD20 scFv h(CD3ζ) CARNK, pCDCAR1 Human rituximab Chimeric scFv-CD3ζ Lentiviral NK cell   Add to Cart   Datasheet
CAR-NK-2-M327-2Z Anti-CD20 scFv h(CD28-CD3ζ) CARNK, pCDCAR1 Human rituximab Chimeric scFv-CD28-CD3ζ Lentiviral NK cell   Add to Cart   Datasheet
CAR-NK-2-M327-4G Anti-CD20 scFv h(CD4-FcεRIγ) CARNK, pCDCAR1 Human rituximab Chimeric scFv-CD4-FcεRIγ Lentiviral NK cell   Add to Cart   Datasheet
CAR-NK-2-M327-4Z Anti-CD20 scFv h(CD4-CD3ζ) CARNK, pCDCAR1 Human rituximab Chimeric scFv-CD4-CD3ζ Lentiviral NK cell   Add to Cart   Datasheet
CAR-NK-2-M327-8Z Anti-CD20 scFv h(CD8-CD3ζ) CARNK, pCDCAR1 Human rituximab Chimeric scFv-CD8-CD3ζ Lentiviral NK cell   Add to Cart   Datasheet
CAR-NK-2-M327-BG Anti-CD20 scFv h(CD28-FcεRIγ) CARNK, pCDCAR1 Human rituximab Chimeric scFv-CD28-FcεRIγ Lentiviral NK cell   Add to Cart   Datasheet
CAR-LC227 Anti-CD20 h(41BB-CD3ζ) CAR, pCDCAR1 Human Mouse scFv-41BB-CD3ζ Lentiviral NK cell   Add to Cart   Datasheet
CAR-LC354 Anti-MS4A1 h(41BB-CD3ζ, Her2t) Marked CAR, pCDCAR1 Human Human scFv-41BB-CD3ζ/Her2t Lentiviral T cell   Add to Cart   Datasheet
CAR-NK-2-M327-BZ Anti-CD20 scFv h(41BB-CD3ζ) CARNK, pCDCAR1 Human rituximab Chimeric scFv-41BB-CD3ζ Lentiviral NK cell   Add to Cart   Datasheet
CAR-MZ017 Anti-CD20 (Leu-16) h(CD3ζ) CAR, pCDCAR1 Human Leu-16 Human scFv-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-T-1-M302-2 Anti-CD20 scFv h(CD28) CART, pCDCAR1 Human 1F5 Mouse scFv-CD28 Lentiviral T cell   Add to Cart   Datasheet
CAR-T-1-M302-G Anti-CD20 scFv h(FcεRIγ) CART, pCDCAR1 Human 1F5 Mouse scFv-FcεRIγ Lentiviral T cell   Add to Cart   Datasheet
CAR-T-1-M302-Z Anti-CD20 scFv h(CD3ζ) CART, pCDCAR1 Human 1F5 Mouse scFv-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-T-2-M302-2G Anti-CD20 scFv h(CD28-FcεRIγ) CART, pCDCAR1 Human 1F5 Mouse scFv-CD28-FcεRIγ Lentiviral T cell   Add to Cart   Datasheet
CAR-T-2-M302-2Z Anti-CD20 scFv h(CD28-CD3ζ) CART, pCDCAR1 Human 1F5 Mouse scFv-CD28-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-T-2-M302-4G Anti-CD20 scFv h(CD4-FcεRIγ) CART, pCDCAR1 Human 1F5 Mouse scFv-CD4-FcεRIγ Lentiviral T cell   Add to Cart   Datasheet
CAR-T-2-M302-4Z Anti-CD20 scFv h(CD4-CD3ζ) CART, pCDCAR1 Human 1F5 Mouse scFv-CD4-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-T-2-M302-8Z Anti-CD20 scFv h(CD8-CD3ζ) CART, pCDCAR1 Human 1F5 Mouse scFv-CD8-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-T-2-M302-BZ Anti-CD20 scFv h(41BB-CD3ζ) CART, pCDCAR1 Human 1F5 Mouse scFv-41BB-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-T-2-M302-CZ Anti-CD20 scFv h(b2c-CD3ζ) CART, pCDCAR1 Human 1F5 Mouse scFv-b2c-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-T-3-M302-2BZ Anti-CD20 scFv h(CD28-41BB-CD3ζ) CART, pCDCAR1 Human 1F5 Mouse scFv-CD28-41BB-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-T-3-M302-2XZ Anti-CD20 scFv h(CD28-OX40-CD3ζ) CART, pCDCAR1 Human 1F5 Mouse scFv-CD28-OX40-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-MZ018 Anti-CD20 (Leu-16) h(CD28-4-1BB-CD3ζ) CAR, pCDCAR1 Human Leu-16 Mouse scFv-CD28-41BB-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
CAR-MZ055 Anti-CD20 (Ofatumumab) h(FcγRIII) CAR, pCDCAR1 Human Ofatumumab Human scFv-FcγRIII Lentiviral NK cell   Add to Cart   Datasheet
CAR-MZ056 Anti-CD20 (Ofatumumab) h(CD3ζ) CAR, pCDCAR1 Human Ofatumumab Human scFv-CD3ζ Lentiviral NK cell   Add to Cart   Datasheet
CAR-MZ057 Anti-CD20 (Ofatumumab) h(CD28-CD3ζ) CAR, pCDCAR1 Human Ofatumumab Human scFv-CD28-CD3ζ Lentiviral NK cell   Add to Cart   Datasheet
CAR-YF011 Anti-CD20 (Ofatumumab) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human Ofatumumab Human scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-YF012 Anti-CD20 (Ofatumumab) h(CD28-CD3ζ) CAR, pCDCAR1 Human Ofatumumab Human scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-YF013 Anti-CD20 (Rituximab) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human Rituximab Mouse scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-YF014 Anti-CD20 (Rituximab) h(CD28-CD3ζ) CAR, pCDCAR1 Human Rituximab Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-YF015 Anti-CD20 (Obinutuzumab) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human Obinutuzumab Human scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-YF016 Anti-CD20 (Obinutuzumab) h(CD28-CD3ζ) CAR, pCDCAR1 Human Obinutuzumab Human scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-YF399 Anti-CD20 (2H7) h(-CD3ζ) CAR, pCDCAR1 Human 2H7 Mouse scFv-CD3ζ Lentiviral vector T Cell   Add to Cart   Datasheet
CAR-YF400 Anti-CD20 (2H7) h(CD28-CD3ζ) CAR, pCDCAR1 Human 2H7 Mouse scFv-CD28-CD3ζ Lentiviral vector T Cell   Add to Cart   Datasheet
CAR-YF402 Anti-CD20 (2H7) h(CD28-41BB-CD3ζ) CAR, pCDCAR1 Human 2H7 Mouse scFv-CD28-41BB-CD3ζ Lentiviral vector T Cell   Add to Cart   Datasheet

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