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EXPOLORE MORECreative Biolabs has a tradition of commitment. To achieve efficient execution and regulatory approval, we offer careful considerations of your program for the development of a cellular or gene therapy product – now and in the future.
EXPOLORE MOREWe focus on unmet needs and develop novel cellular and gene drugs and solutions that offer significant benefits over existing options.
EXPOLORE MORETo accelerate advanced breakthroughs of your projects, we offer broad range of platforms which enable our clients be free to tackle problems with cutting-edge technologies from different angles and in different methods.
EXPOLORE MOREUse the resources in our library to help you understand your options and make critical decisions for your study. We offer oncolytic virus, CAR-T, and dendritic cell related documents, as well as newsletter. If you don’t find the answers you’re looking for, contact us for additional assistance.
EXPOLORE MORECD20 (Cluster of Differentiation 20), also called B lymphocyte antigen CD20, is an activated-glycosylated phosphoprotein expressed on the surface of all B-cells, in human it is encoded by MS4A1 gene. CD20 plays a role in the development and differentiation of B-cells into plasma cells.its function is to enable optimal B-cell immune response, specifically against T-independent antigens.CD20 is expressed on all stages of B cell development except the first and last. It has been found that associated with B-cell lymphomas, hairy cell leukemia, B-cell chronic lymphocytic leukemia, and melanoma cancer stem cells. Therefore CD20 have been considered as a therapeutic target of monoclonal antibodies such as rituximab, obinutuzumab, Ibritumomab tiuxetan, and tositumomab, which are all active agents in the treatment of all B cell lymphomas and leukemias.
Associated Disease
Loading...| CAT | Product Name | Target Species | Antibody Clone | Antibody Host | Receptor Construction | Vector Type | Targeting Cell Type | Inquiry & Datasheet |
| CAR-NK-1-M327-2 | Anti-CD20 scFv h(CD28) CARNK, pCDCAR1 | Human | rituximab | Chimeric | scFv-CD28 | Lentiviral | NK cell | |
| CAR-NK-1-M327-G | Anti-CD20 scFv h(FcεRIγ) CARNK, pCDCAR1 | Human | rituximab | Chimeric | scFv-FcεRIγ | Lentiviral | NK cell | |
| CAR-NK-1-M327-Z | Anti-CD20 scFv h(CD3ζ) CARNK, pCDCAR1 | Human | rituximab | Chimeric | scFv-CD3ζ | Lentiviral | NK cell | |
| CAR-NK-2-M327-2Z | Anti-CD20 scFv h(CD28-CD3ζ) CARNK, pCDCAR1 | Human | rituximab | Chimeric | scFv-CD28-CD3ζ | Lentiviral | NK cell | |
| CAR-NK-2-M327-CZ | Anti-CD20 scFv h(b2c-CD3ζ) CARNK, pCDCAR1 | Human | rituximab | Chimeric | scFv-b2c-CD3ζ | Lentiviral | NK cell | |
| CAR-NK-3-M327-2BZ | Anti-CD20 scFv h(CD28-41BB-CD3ζ) CARNK, pCDCAR1 | Human | rituximab | Chimeric | scFv-CD28-41BB-CD3ζ | Lentiviral | NK cell | |
| CAR-NK-2-M327-4G | Anti-CD20 scFv h(CD4-FcεRIγ) CARNK, pCDCAR1 | Human | rituximab | Chimeric | scFv-CD4-FcεRIγ | Lentiviral | NK cell | |
| CAR-NK-2-M327-4Z | Anti-CD20 scFv h(CD4-CD3ζ) CARNK, pCDCAR1 | Human | rituximab | Chimeric | scFv-CD4-CD3ζ | Lentiviral | NK cell | |
| CAR-NK-3-M327-2XZ | Anti-CD20 scFv h(CD28-OX40-CD3ζ) CARNK, pCDCAR1 | Human | rituximab | Chimeric | scFv-CD28-OX40-CD3ζ | Lentiviral | NK cell | |
| CAR-NK-2-M327-8Z | Anti-CD20 scFv h(CD8-CD3ζ) CARNK, pCDCAR1 | Human | rituximab | Chimeric | scFv-CD8-CD3ζ | Lentiviral | NK cell | |
| CAR-NK-2-M327-BG | Anti-CD20 scFv h(CD28-FcεRIγ) CARNK, pCDCAR1 | Human | rituximab | Chimeric | scFv-CD28-FcεRIγ | Lentiviral | NK cell | |
| CAR-T-1-M302-2 | Anti-CD20 scFv h(CD28) CART, pCDCAR1 | Human | 1F5 | Mouse | scFv-CD28 | Lentiviral | T cell | |
| CAR-T-1-M302-G | Anti-CD20 scFv h(FcεRIγ) CART, pCDCAR1 | Human | 1F5 | Mouse | scFv-FcεRIγ | Lentiviral | T cell | |
| CAR-LC227 | Anti-CD20 h(41BB-CD3ζ) CAR, pCDCAR1 | Human | Mouse | scFv-41BB-CD3ζ | Lentiviral | NK cell | ||
| CAR-LC354 | Anti-MS4A1 h(41BB-CD3ζ, Her2t) Marked CAR, pCDCAR1 | Human | Human | scFv-41BB-CD3ζ/Her2t | Lentiviral | T cell | ||
| CAR-MZ017 | Anti-CD20 (Leu-16) h(CD3ζ) CAR, pCDCAR1 | Human | Leu-16 | Human | scFv-CD3ζ | Lentiviral | T cell | |
| CAR-MZ018 | Anti-CD20 (Leu-16) h(CD28-4-1BB-CD3ζ) CAR, pCDCAR1 | Human | Leu-16 | Mouse | scFv-CD28-41BB-CD3ζ | Lentiviral | T cell | |
| CAR-T-1-M302-Z | Anti-CD20 scFv h(CD3ζ) CART, pCDCAR1 | Human | 1F5 | Mouse | scFv-CD3ζ | Lentiviral | T cell | |
| CAR-T-2-M302-2G | Anti-CD20 scFv h(CD28-FcεRIγ) CART, pCDCAR1 | Human | 1F5 | Mouse | scFv-CD28-FcεRIγ | Lentiviral | T cell | |
| CAR-T-2-M302-2Z | Anti-CD20 scFv h(CD28-CD3ζ) CART, pCDCAR1 | Human | 1F5 | Mouse | scFv-CD28-CD3ζ | Lentiviral | T cell | |
| CAR-T-2-M302-4G | Anti-CD20 scFv h(CD4-FcεRIγ) CART, pCDCAR1 | Human | 1F5 | Mouse | scFv-CD4-FcεRIγ | Lentiviral | T cell | |
| CAR-T-2-M302-4Z | Anti-CD20 scFv h(CD4-CD3ζ) CART, pCDCAR1 | Human | 1F5 | Mouse | scFv-CD4-CD3ζ | Lentiviral | T cell | |
| CAR-T-2-M302-8Z | Anti-CD20 scFv h(CD8-CD3ζ) CART, pCDCAR1 | Human | 1F5 | Mouse | scFv-CD8-CD3ζ | Lentiviral | T cell | |
| CAR-T-2-M302-BZ | Anti-CD20 scFv h(41BB-CD3ζ) CART, pCDCAR1 | Human | 1F5 | Mouse | scFv-41BB-CD3ζ | Lentiviral | T cell | |
| CAR-T-2-M302-CZ | Anti-CD20 scFv h(b2c-CD3ζ) CART, pCDCAR1 | Human | 1F5 | Mouse | scFv-b2c-CD3ζ | Lentiviral | T cell | |
| CAR-T-3-M302-2BZ | Anti-CD20 scFv h(CD28-41BB-CD3ζ) CART, pCDCAR1 | Human | 1F5 | Mouse | scFv-CD28-41BB-CD3ζ | Lentiviral | T cell | |
| CAR-T-3-M302-2XZ | Anti-CD20 scFv h(CD28-OX40-CD3ζ) CART, pCDCAR1 | Human | 1F5 | Mouse | scFv-CD28-OX40-CD3ζ | Lentiviral | T cell | |
| CAR-NK-2-M327-BZ | Anti-CD20 scFv h(41BB-CD3ζ) CARNK, pCDCAR1 | Human | rituximab | Chimeric | scFv-41BB-CD3ζ | Lentiviral | NK cell | |
| CAR-MZ058 | Anti-CD20 (Ofatumumab) h(41BB-CD3ζ) CAR, pCDCAR1 | Human | Ofatumumab | Human | scFv-41BB-CD3ζ | Lentiviral | NK cell | |
| CAR-LY1718 | Anti-CD20(2H7) h(CD28-CD3ζ) CAR, pCDCAR1 | Human, Monkey | 2H7 | Mouse | scFv-CD28-CD3ζ | Lentiviral vector | T cell | |
| CAR-YF011 | Anti-CD20 (Ofatumumab) h(4-1BB-CD3ζ) CAR, pCDCAR1 | Human | Ofatumumab | Human | scFv-4-1BB-CD3ζ | Lentiviral vector | T cell | |
| CAR-YF012 | Anti-CD20 (Ofatumumab) h(CD28-CD3ζ) CAR, pCDCAR1 | Human | Ofatumumab | Human | scFv-CD28-CD3ζ | Lentiviral vector | T cell | |
| CAR-YF013 | Anti-CD20 (Rituximab) h(4-1BB-CD3ζ) CAR, pCDCAR1 | Human | Rituximab | Mouse | scFv-4-1BB-CD3ζ | Lentiviral vector | T cell | |
| CAR-YF014 | Anti-CD20 (Rituximab) h(CD28-CD3ζ) CAR, pCDCAR1 | Human | Rituximab | Mouse | scFv-CD28-CD3ζ | Lentiviral vector | T cell | |
| CAR-YF015 | Anti-CD20 (Obinutuzumab) h(4-1BB-CD3ζ) CAR, pCDCAR1 | Human | Obinutuzumab | Human | scFv-4-1BB-CD3ζ | Lentiviral vector | T cell | |
| CAR-YF016 | Anti-CD20 (Obinutuzumab) h(CD28-CD3ζ) CAR, pCDCAR1 | Human | Obinutuzumab | Human | scFv-CD28-CD3ζ | Lentiviral vector | T cell | |
| CAR-MZ055 | Anti-CD20 (Ofatumumab) h(FcγRIII) CAR, pCDCAR1 | Human | Ofatumumab | Human | scFv-FcγRIII | Lentiviral | NK cell | |
| CAR-MZ056 | Anti-CD20 (Ofatumumab) h(CD3ζ) CAR, pCDCAR1 | Human | Ofatumumab | Human | scFv-CD3ζ | Lentiviral | NK cell | |
| CAR-MZ057 | Anti-CD20 (Ofatumumab) h(CD28-CD3ζ) CAR, pCDCAR1 | Human | Ofatumumab | Human | scFv-CD28-CD3ζ | Lentiviral | NK cell | |
| CAR-LY078 | Anti-CD20 (2H7) h(41BB-CD3ζ) CAR, pCDCAR1 | Human, Monkey | 2H7 | Mouse | scFv-41BB-CD3ζ | Lentiviral vector | T cell |
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