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CEP290

All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

This gene encodes a protein with 13 putative coiled-coil domains, a region with homology to SMC chromosome segregation ATPases, six KID motifs, three tropomyosin homology domains and an ATP/GTP binding site motif A. The protein is localized to the centrosome and cilia and has sites for N-glycosylation, tyrosine sulfation, phosphorylation, N-myristoylation, and amidation. Mutations in this gene have been associated with Joubert syndrome and nephronophthisis and the presence of antibodies against this protein is associated with several forms of cancer. [provided by RefSeq, Jul 2008]
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CAT Product Name Target Species Antibody Clone Antibody Host Receptor Construction Vector Type Targeting Cell Type CAR Vector Type Inquiry & Datasheet
CAR-ZP134 Anti-CEP290 (3H11) h(CD28-CD3ζ) CAR, pCDCAR1 Mouse Human 3H11 scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP135 Anti-CEP290 (3H11) h(41BB-CD3ζ) CAR, pCDCAR1 Mouse Human 3H11 scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP5893 Anti-CEP290 (1F3G10) h(CD28-CD3ζ) CAR, pCDCAR1 Mouse Human 1F3G10 scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP5894 Anti-CEP290 (1F3G10) h(41BB-CD3ζ) CAR, pCDCAR1 Mouse Human 1F3G10 scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
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