CLDN18.2

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This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This gene is upregulated in patients with ulcerative colitis and highly overexpressed in infiltrating ductal adenocarcinomas. PKC/MAPK/AP1 (protein kinase C/mitogenactivated protein kinase/activator protein1) dependent pathway regulates the expression of this gene in gastric cells. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jun 2010]
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CAT Product Name Target Species Antibody Clone Antibody Host Receptor Construction Vector Type Targeting Cell Type CAR Vector Type Inquiry & Datasheet
XS-0722-ZP4647 Anti-CLDN18.2 (hu8E5) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human hu8E5 Humanized scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0722-ZP4648 Anti-CLDN18.2 (hu8E5-2I) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human hu8E5-2I Humanized scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0822-YF8767 TS-Fluc Anti-Human CLDN18.2 scFv (XW-276) 41BB-CD3ζ CAR, pCDCAR1 Human XW-276 Mouse 7H-YB-Fluc-EF1a-scFv-41BB-CD3ζ Lentiviral vector   Add to Cart   Datasheet
XS-0822-YF8768 TS-Fluc Anti-Mouse CLDN18.2 scFv (XW-277) 41BB-CD3ζ CAR, pCDCAR1 Mouse XW-277 Rat 7H-YB-Fluc-EF1a-scFv-41BB-CD3ζ Lentiviral vector   Add to Cart   Datasheet
XS-0822-YF8769 TS-Fluc Anti-Human CLDN18.2 scFv (XW-278) 41BB-CD3ζ CAR, pCDCAR1 Human XW-278 Mouse 7H-YB-Fluc-EF1a-scFv-41BB-CD3ζ Lentiviral vector   Add to Cart   Datasheet
XS-0822-YF8770 TS-Fluc Anti-Human CLDN18.2 scFv (XW-279) 41BB-CD3ζ CAR, pCDCAR1 Human XW-279 Mouse 7H-YB-Fluc-EF1a-scFv-41BB-CD3ζ Lentiviral vector   Add to Cart   Datasheet
XS-0822-YF8771 TS-Fluc Anti-Human CLDN18.2 scFv (XW-280) 41BB-CD3ζ CAR, pCDCAR1 Human XW-280 Mouse 7H-YB-Fluc-EF1a-scFv-41BB-CD3ζ Lentiviral vector   Add to Cart   Datasheet
XS-0822-YF8772 TS-Fluc Anti-Mouse CLDN18.2 scFv (XW-281) 41BB-CD3ζ CAR, pCDCAR1 Mouse XW-281 Rat 7H-YB-Fluc-EF1a-scFv-41BB-CD3ζ Lentiviral vector   Add to Cart   Datasheet
XS-0822-YF8773 TS-Fluc Anti-Human CLDN18.2 scFv (XW-282) 41BB-CD3ζ CAR, pCDCAR1 Human XW-282 Mouse 7H-YB-Fluc-EF1a-scFv-41BB-CD3ζ Lentiviral vector   Add to Cart   Datasheet
XS-0822-YF8774 TS-Fluc Anti-Human CLDN18.2 scFv (XW-283) 41BB-CD3ζ CAR, pCDCAR1 Human XW-283 Humanized 7H-YB-Fluc-EF1a-scFv-41BB-CD3ζ Lentiviral vector   Add to Cart   Datasheet
XS-0822-YF8775 TS-Fluc Anti-Human CLDN18.2 scFv (XW-284) 41BB-CD3ζ CAR, pCDCAR1 Human XW-284 Humanized 7H-YB-Fluc-EF1a-scFv-41BB-CD3ζ Lentiviral vector   Add to Cart   Datasheet
XS-0822-YF8776 TS-Fluc Anti-Human CLDN18.2 scFv (XW-285) 41BB-CD3ζ CAR, pCDCAR1 Human XW-285 Mouse 7H-YB-Fluc-EF1a-scFv-41BB-CD3ζ Lentiviral vector   Add to Cart   Datasheet
XS-0822-YF9176 TS-Fluc Anti-Human CLDN18.2 scFv (XW-276) CD28-41BB-CD3ζ CAR, pCDCAR1 Human XW-276 Mouse 7H-YB-Fluc-EF1a-scFv-CD28-41BB-CD3ζ Lentiviral vector   Add to Cart   Datasheet
XS-0822-YF9177 TS-Fluc Anti-Mouse CLDN18.2 scFv (XW-277) CD28-41BB-CD3ζ CAR, pCDCAR1 Mouse XW-277 Rat 7H-YB-Fluc-EF1a-scFv-CD28-41BB-CD3ζ Lentiviral vector   Add to Cart   Datasheet
XS-0822-YF9178 TS-Fluc Anti-Human CLDN18.2 scFv (XW-278) CD28-41BB-CD3ζ CAR, pCDCAR1 Human XW-278 Mouse 7H-YB-Fluc-EF1a-scFv-CD28-41BB-CD3ζ Lentiviral vector   Add to Cart   Datasheet
XS-0822-YF9179 TS-Fluc Anti-Human CLDN18.2 scFv (XW-279) CD28-41BB-CD3ζ CAR, pCDCAR1 Human XW-279 Mouse 7H-YB-Fluc-EF1a-scFv-CD28-41BB-CD3ζ Lentiviral vector   Add to Cart   Datasheet
XS-0822-YF9180 TS-Fluc Anti-Human CLDN18.2 scFv (XW-280) CD28-41BB-CD3ζ CAR, pCDCAR1 Human XW-280 Mouse 7H-YB-Fluc-EF1a-scFv-CD28-41BB-CD3ζ Lentiviral vector   Add to Cart   Datasheet
XS-0822-YF9181 TS-Fluc Anti-Mouse CLDN18.2 scFv (XW-281) CD28-41BB-CD3ζ CAR, pCDCAR1 Mouse XW-281 Rat 7H-YB-Fluc-EF1a-scFv-CD28-41BB-CD3ζ Lentiviral vector   Add to Cart   Datasheet
XS-0822-YF9182 TS-Fluc Anti-Human CLDN18.2 scFv (XW-282) CD28-41BB-CD3ζ CAR, pCDCAR1 Human XW-282 Mouse 7H-YB-Fluc-EF1a-scFv-CD28-41BB-CD3ζ Lentiviral vector   Add to Cart   Datasheet
XS-0822-YF9183 TS-Fluc Anti-Human CLDN18.2 scFv (XW-283) CD28-41BB-CD3ζ CAR, pCDCAR1 Human XW-283 Humanized 7H-YB-Fluc-EF1a-scFv-CD28-41BB-CD3ζ Lentiviral vector   Add to Cart   Datasheet
XS-0823-LX29 Anti-hCLDN18.2 (182511) ICD(CD28-OX40-CD3ζ) CAR-MA, pAd5f35 Vector Human 182511 Adenoviral vectors   Add to Cart   Datasheet
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