CLDN18.2

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This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This gene is upregulated in patients with ulcerative colitis and highly overexpressed in infiltrating ductal adenocarcinomas. PKC/MAPK/AP1 (protein kinase C/mitogenactivated protein kinase/activator protein1) dependent pathway regulates the expression of this gene in gastric cells. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jun 2010]
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CAT Product Name Target Species Antibody Clone Antibody Host Receptor Construction Vector Type Targeting Cell Type CAR Vector Type Inquiry & Datasheet
XS-0822-YF10409 TS-IL15 SA Anti-Human CLDN18.2 scFv (XW-282) CD28-41BB-CD3ζ CAR, pCDCAR1 Human XW-282 Mouse 7H-YB-IL15 SA-EF1a-scFv-CD28-41BB-CD3ζ Lentiviral vector   Add to Cart   Datasheet
XS-0822-YF10410 TS-IL15 SA Anti-Human CLDN18.2 scFv (XW-283) CD28-41BB-CD3ζ CAR, pCDCAR1 Human XW-283 Humanized 7H-YB-IL15 SA-EF1a-scFv-CD28-41BB-CD3ζ Lentiviral vector   Add to Cart   Datasheet
XS-0822-YF10411 TS-IL15 SA Anti-Human CLDN18.2 scFv (XW-284) CD28-41BB-CD3ζ CAR, pCDCAR1 Human XW-284 Humanized 7H-YB-IL15 SA-EF1a-scFv-CD28-41BB-CD3ζ Lentiviral vector   Add to Cart   Datasheet
XS-0822-YF10412 TS-IL15 SA Anti-Human CLDN18.2 scFv (XW-285) CD28-41BB-CD3ζ CAR, pCDCAR1 Human XW-285 Mouse 7H-YB-IL15 SA-EF1a-scFv-CD28-41BB-CD3ζ Lentiviral vector   Add to Cart   Datasheet
XS-0922-ZP825 Anti-CLDN18.2 (claudiximab) h(CD28-CD3ζ) CAR, pCDCAR1 Human claudiximab Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0922-ZP869 Anti-CLDN18.2 (CB-P05) h(CD28-CD3ζ) CAR, pCDCAR1 Mouse CB-P05 Rat scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0922-ZP1062 Anti-CLDN18.2 (5C9) h(CD28-CD3ζ) CAR, pCDCAR1 Human 5C9 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0922-ZP1065 Anti-CLDN18.2 (Ab10) h(CD28-CD3ζ) CAR, pCDCAR1 Human Ab10 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0922-ZP1135 Anti-CLDN18.2 (claudiximab) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human claudiximab Mouse scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0922-ZP1179 Anti-CLDN18.2 (CB-P05) h(4-1BB-CD3ζ) CAR, pCDCAR1 Mouse CB-P05 Rat scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0922-ZP1372 Anti-CLDN18.2 (5C9) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human 5C9 Mouse scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0922-ZP1375 Anti-CLDN18.2 (Ab10) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human Ab10 Mouse scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-1122-YF276 Anti-CLDN18.2 KIR CAR (scFv-KIR2DS2-DAP12, XW-276), pCDCAR1 Human XW-276 Mouse scFv-KIR2DS2 TM&ICD-2A-DAP12 Lentiviral vector T Cell   Add to Cart   Datasheet
XS-1122-YF277 Anti-CLDN18.2 KIR CAR (scFv-KIR2DS2-DAP12, XW-277), pCDCAR1 Mouse XW-277 Rat scFv-KIR2DS2 TM&ICD-2A-DAP12 Lentiviral vector T Cell   Add to Cart   Datasheet
XS-1122-YF278 Anti-CLDN18.2 KIR CAR (scFv-KIR2DS2-DAP12, XW-278), pCDCAR1 Human XW-278 Mouse scFv-KIR2DS2 TM&ICD-2A-DAP12 Lentiviral vector T Cell   Add to Cart   Datasheet
XS-1122-YF279 Anti-CLDN18.2 KIR CAR (scFv-KIR2DS2-DAP12, XW-279), pCDCAR1 Human XW-279 Mouse scFv-KIR2DS2 TM&ICD-2A-DAP12 Lentiviral vector T Cell   Add to Cart   Datasheet
XS-1122-YF280 Anti-CLDN18.2 KIR CAR (scFv-KIR2DS2-DAP12, XW-280), pCDCAR1 Human XW-280 Mouse scFv-KIR2DS2 TM&ICD-2A-DAP12 Lentiviral vector T Cell   Add to Cart   Datasheet
XS-1122-YF281 Anti-CLDN18.2 KIR CAR (scFv-KIR2DS2-DAP12, XW-281), pCDCAR1 Mouse XW-281 Rat scFv-KIR2DS2 TM&ICD-2A-DAP12 Lentiviral vector T Cell   Add to Cart   Datasheet
XS-1122-YF282 Anti-CLDN18.2 KIR CAR (scFv-KIR2DS2-DAP12, XW-282), pCDCAR1 Human XW-282 Mouse scFv-KIR2DS2 TM&ICD-2A-DAP12 Lentiviral vector T Cell   Add to Cart   Datasheet
XS-1122-YF285 Anti-CLDN18.2 KIR CAR (scFv-KIR2DS2-DAP12, XW-285), pCDCAR1 Human XW-285 Mouse scFv-KIR2DS2 TM&ICD-2A-DAP12 Lentiviral vector T Cell   Add to Cart   Datasheet
XS-0823-LX29 Anti-hCLDN18.2 (182511) ICD(CD28-OX40-CD3ζ) CAR-MA, pAd5f35 Vector Human 182511 Adenoviral vectors   Add to Cart   Datasheet
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