CLDN18A2

CLDN18A2 is the stomach isoform of CLDN18. CLDN18 is a protein that in humans is encoded by CLDN18 gene. It belongs to the group of claudins, a large family of proteins which form tight junction strands in epithelial cells. Since claudin-18 (Cldn18) is overexpressed in precursor lesion PanIN and pancreatic duct carcinoma, it serves as a diagnostic marker and a target of immunotherapy.

Associated Disease

CAR Vector Products Product list:

Catalog Targeting
Cell Type
Generation Antibody
Clone
Vector
Length
Vector
Type
Vector Design Antibody
Host
Data
sheet
Price
CAR-LC199 T cell First 163 ~8kb Lentiviral scFv-CD3ζ Mouse Inquiry
CAR-LC200 T cell Third 163 ~8kb Lentiviral scFv-CD28-41BB-CD3ζ Mouse Inquiry
CAR-LC201 T cell First 175 ~8kb Lentiviral scFv-CD3ζ Mouse Inquiry
CAR-LC202 T cell Third 175 ~8kb Lentiviral scFv-CD28-41BB-CD3ζ Mouse Inquiry

CAR Viral Particles Product list:

Catalog Antibody
Clone
Packaging
System
Generation Gene
Construct
Promotor Packaging
Cell
Titer Data
sheet
Price
VP-CAR-LC677 163 Lentivirus First scFv (163)-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC678 163 Lentivirus Second scFv (163)-CD28-41BB-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC679 175 Lentivirus First scFv (175)-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC680 175 Lentivirus Second scFv (175)-CD28-41BB-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
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