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DUSP12

All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

DUSP12 is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product is the human ortholog of the Saccharomyces cerevisiae YVH1 protein tyrosine phosphatase. It is localized predominantly in the nucleus, and is novel in that it contains, and is regulated by a zinc finger domain.
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CAT Product Name Target Species Antibody Clone Antibody Host Receptor Construction Vector Type Targeting Cell Type CAR Vector Type Inquiry & Datasheet
CAR-YC0683 Anti-DUSP12 (AF28B2) h(scFv-41BB-CD3ζ) CAR, pCDCAR1 Human AF28B2 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-YC0684 Anti-DUSP12 (PK15-AF28F3) h(scFv-41BB-CD3ζ) CAR, pCDCAR1 Human PK15-AF28F3 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-YC1583 Anti-DUSP12 (AF28B2) h(scFv-CD28-CD3ζ) CAR, pCDCAR1 Human AF28B2 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-YC1584 Anti-DUSP12 (PK15-AF28F3) h(scFv-CD28-CD3ζ) CAR, pCDCAR1 Human PK15-AF28F3 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
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