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EIF4G2

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Translation initiation is mediated by specific recognition of the cap structure by eukaryotic translation initiation factor 4F (eIF4F), which is a cap binding protein complex that consists of three subunits: eIF4A, eIF4E and eIF4G. The protein encoded by this gene shares similarity with the C-terminal region of eIF4G that contains the binding sites for eIF4A and eIF3; eIF4G, in addition, contains a binding site for eIF4E at the N-terminus. Unlike eIF4G, which supports cap-dependent and independent translation, this gene product functions as a general repressor of translation by forming translationally inactive complexes. In vitro and in vivo studies indicate that translation of this mRNA initiates exclusively at a non-AUG (GUG) codon. Alternatively spliced transcript variants encoding different isoforms of this gene have been described.
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CAT Product Name Target Species Antibody Clone Antibody Host Receptor Construction Vector Type Targeting Cell Type CAR Vector Type Inquiry & Datasheet
CAR-YC0726 Anti-EIF4G2 (39C534.1) h(scFv-41BB-CD3ζ) CAR, pCDCAR1 Human 39C534.1 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-YC0727 Anti-EIF4G2 (XHM150) h(scFv-41BB-CD3ζ) CAR, pCDCAR1 Human XHM150 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-YC0728 Anti-EIF4G2 (CBYCD-471) h(scFv-41BB-CD3ζ) CAR, pCDCAR1 Human CBYCD-471 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-YC1626 Anti-EIF4G2 (39C534.1) h(scFv-CD28-CD3ζ) CAR, pCDCAR1 Human 39C534.1 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-YC1627 Anti-EIF4G2 (XHM150) h(scFv-CD28-CD3ζ) CAR, pCDCAR1 Human XHM150 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-YC1628 Anti-EIF4G2 (CBYCD-471) h(scFv-CD28-CD3ζ) CAR, pCDCAR1 Human CBYCD-471 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY0196 Anti-EIF4G2 (CBFYE-0738) h(41BB-CD3ζ) CAR, pCDCAR1 Human, Mouse CBFYE-0738 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY0197 Anti-EIF4G2 (CBFYE-0739) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBFYE-0739 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY0198 Anti-EIF4G2 (CBFYE-0740) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBFYE-0740 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY0199 Anti-EIF4G2 (CBFYE-0741) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBFYE-0741 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY3449 Anti-EIF4G2 (CBFYE-0738) h(CD28-CD3ζ) CAR, pCDCAR1 Human, Mouse CBFYE-0738 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY3450 Anti-EIF4G2 (CBFYE-0739) h(CD28-CD3ζ) CAR, pCDCAR1 Human CBFYE-0739 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY3451 Anti-EIF4G2 (CBFYE-0740) h(CD28-CD3ζ) CAR, pCDCAR1 Human CBFYE-0740 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY3452 Anti-EIF4G2 (CBFYE-0741) h(CD28-CD3ζ) CAR, pCDCAR1 Human CBFYE-0741 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
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