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FGB

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The protein encoded by this gene is the beta component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including afibrinogenemia, dysfibrinogenemia, hypodysfibrinogenemia and thrombotic tendency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2014]
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CAT Product Name Target Species Antibody Clone Antibody Host Receptor Construction Vector Type Targeting Cell Type CAR Vector Type Inquiry & Datasheet
XS-1222-ZP84 FGB (ITGA2B Receptor) h(CD28-CD3ζ) Ligand-based CAR, pCDCAR1 Human FGB-CD28-CD6ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-1222-ZP85 FGB (ITGA5 Receptor) h(CD28-CD3ζ) Ligand-based CAR, pCDCAR1 Human FGB-CD28-CD6ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-1222-ZP86 FGB (ITGAM Receptor) h(CD28-CD3ζ) Ligand-based CAR, pCDCAR1 Human FGB-CD28-CD6ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-1222-ZP87 FGB (ITGAV Receptor) h(CD28-CD3ζ) Ligand-based CAR, pCDCAR1 Human FGB-CD28-CD6ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-1222-ZP88 FGB (ITGB1 Receptor) h(CD28-CD3ζ) Ligand-based CAR, pCDCAR1 Human FGB-CD28-CD6ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-1222-ZP89 FGB (ITGB2 Receptor) h(CD28-CD3ζ) Ligand-based CAR, pCDCAR1 Human FGB-CD28-CD6ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-1222-ZP1484 FGB (ITGA2B Receptor) h(41BB-CD3ζ) Ligand-based CAR, pCDCAR1 Human FGB-41BB-CD6ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-1222-ZP1485 FGB (ITGA5 Receptor) h(41BB-CD3ζ) Ligand-based CAR, pCDCAR1 Human FGB-41BB-CD6ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-1222-ZP1486 FGB (ITGAM Receptor) h(41BB-CD3ζ) Ligand-based CAR, pCDCAR1 Human FGB-41BB-CD6ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-1222-ZP1487 FGB (ITGAV Receptor) h(41BB-CD3ζ) Ligand-based CAR, pCDCAR1 Human FGB-41BB-CD6ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-1222-ZP1488 FGB (ITGB1 Receptor) h(41BB-CD3ζ) Ligand-based CAR, pCDCAR1 Human FGB-41BB-CD6ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-1222-ZP1489 FGB (ITGB2 Receptor) h(41BB-CD3ζ) Ligand-based CAR, pCDCAR1 Human FGB-41BB-CD6ζ Lentiviral vector T cell   Add to Cart   Datasheet
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