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The protein encoded by this gene is an enzymatic component of the tricarboxylic acid (TCA) cycle, or Krebs cycle, and catalyzes the formation of L-malate from fumarate. It exists in both a cytosolic form and an N-terminal extended form, differing only in the translation start site used. The N-terminal extended form is targeted to the mitochondrion, where the removal of the extension generates the same form as in the cytoplasm. It is similar to some thermostable class II fumarases and functions as a homotetramer. Mutations in this gene can cause fumarase deficiency and lead to progressive encephalopathy.
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CAT Product Name Target Species Antibody Clone Antibody Host Receptor Construction Vector Type Targeting Cell Type CAR Vector Type Inquiry & Datasheet
CAR-CQ4382 Anti-FH (CBXF-1088) h(CD28-CD3ζ) CAR, pCDCAR1 Human, Mouse, Rat CBXF-1088 Rabbit scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ4383 Anti-FH (CBXF-0655) h(CD28-CD3ζ) CAR, pCDCAR1 Human CBXF-0655 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ4384 Anti-FH (CBXF-1089) h(CD28-CD3ζ) CAR, pCDCAR1 Human, Mouse, Rat CBXF-1089 Rabbit scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ4385 Anti-FH (CBXF-0656) h(CD28-CD3ζ) CAR, pCDCAR1 Human, Mouse, Rat CBXF-0656 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ4386 Anti-FH (CBXF-0663) h(CD28-CD3ζ) CAR, pCDCAR1 Human, Mouse, Rat CBXF-0663 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ4387 Anti-FH (CBXF-2098) h(CD28-CD3ζ) CAR, pCDCAR1 Human, Mouse, Rat CBXF-2098 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ4388 Anti-FH (1F10) h(CD28-CD3ζ) CAR, pCDCAR1 Human, Dog, Rat 1F10 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ4389 Anti-FH (CBXF-0661) h(CD28-CD3ζ) CAR, pCDCAR1 Human, Rat, Cattle CBXF-0661 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ4390 Anti-FH (CBXF-0667) h(CD28-CD3ζ) CAR, pCDCAR1 Human, Mouse, Rat CBXF-0667 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ4391 Anti-FH (CBXF-3754) h(CD28-CD3ζ) CAR, pCDCAR1 Human, Dog CBXF-3754 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ4392 Anti-FH (CBXF-2063) h(CD28-CD3ζ) CAR, pCDCAR1 Human, Mouse, Rat, Hamster, Monkey CBXF-2063 Rabbit scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ4393 Anti-FH (CBXF-3584) h(CD28-CD3ζ) CAR, pCDCAR1 Human CBXF-3584 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ4394 Anti-FH (CBXF-0664) h(CD28-CD3ζ) CAR, pCDCAR1 Human, Mouse, Rat CBXF-0664 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ4395 Anti-FH (AT3F6) h(CD28-CD3ζ) CAR, pCDCAR1 Human AT3F6 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ4396 Anti-FH (CBXF-0666) h(CD28-CD3ζ) CAR, pCDCAR1 Human CBXF-0666 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ4397 Anti-FH (CBXF-1840) h(CD28-CD3ζ) CAR, pCDCAR1 Human, Rat, Mouse CBXF-1840 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ4398 Anti-FH (CBXF-1883) h(CD28-CD3ζ) CAR, pCDCAR1 Human CBXF-1883 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ4399 Anti-FH (CBXF-3007) h(CD28-CD3ζ) CAR, pCDCAR1 Human CBXF-3007 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ4400 Anti-FH (CBXF-3008) h(CD28-CD3ζ) CAR, pCDCAR1 Human CBXF-3008 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ4401 Anti-FH (CBXF-3009) h(CD28-CD3ζ) CAR, pCDCAR1 Human CBXF-3009 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
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