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FOLH1

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This gene encodes a type II transmembrane glycoprotein belonging to the M28 peptidase family. The protein acts as a glutamate carboxypeptidase on different alternative substrates, including the nutrient folate and the neuropeptide N-acetyl-l-aspartyl-l-glutamate and is expressed in a number of tissues such as prostate, central and peripheral nervous system and kidney. A mutation in this gene may be associated with impaired intestinal absorption of dietary folates, resulting in low blood folate levels and consequent hyperhomocysteinemia. Expression of this protein in the brain may be involved in a number of pathological conditions associated with glutamate excitotoxicity. In the prostate the protein is up-regulated in cancerous cells and is used as an effective diagnostic and prognostic indicator of prostate cancer. This gene likely arose from a duplication event of a nearby chromosomal region. Alternative splicing gives rise to multiple transcript variants encoding several different isoforms.
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CAT Product Name Target Species Antibody Clone Antibody Host Receptor Construction Vector Type Targeting Cell Type CAR Vector Type Inquiry & Datasheet
XS-0722-LX89 Anti-FOLH1 (X7X89) h(CD28-41BB-CD3ζ) CAR, pSBCAR1 human X7X89 Humanized scFv-CD28-41BB-CD3ζ Sleeping Beauty (SB) transposon T cell   Add to Cart   Datasheet
XS-0722-LX90 Anti-FOLH1 (X7X90) h(CD28-41BB-CD3ζ) CAR, pSBCAR1 human X7X90 Humanized scFv-CD28-41BB-CD3ζ Sleeping Beauty (SB) transposon T cell   Add to Cart   Datasheet
XS-0722-LX91 Anti-FOLH1 (X7X91) h(CD28-41BB-CD3ζ) CAR, pSBCAR1 human X7X91 Humanized scFv-CD28-41BB-CD3ζ Sleeping Beauty (SB) transposon T cell   Add to Cart   Datasheet
XS-0722-LX92 Anti-FOLH1 (X7X92) h(CD28-41BB-CD3ζ) CAR, pSBCAR1 human X7X92 Humanized scFv-CD28-41BB-CD3ζ Sleeping Beauty (SB) transposon T cell   Add to Cart   Datasheet
XS-0722-LX130 Anti-FOLH1 (X7X130) h(CD28-41BB-CD3ζ) CAR, pSBCAR1 human X7X130 human scFv-CD28-41BB-CD3ζ Sleeping Beauty (SB) transposon T cell   Add to Cart   Datasheet
XS-0722-LX131 Anti-FOLH1 (X7X131) h(CD28-41BB-CD3ζ) CAR, pSBCAR1 human X7X131 human scFv-CD28-41BB-CD3ζ Sleeping Beauty (SB) transposon T cell   Add to Cart   Datasheet
XS-0722-LX491 Anti-FOLH1 (X7X75) h(ICOS-4-1BB-CD3ζ) CAR, pCDCAR1 human X7X75 human scFv-ICOS-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0722-LX492 Anti-FOLH1 (X7X76) h(ICOS-4-1BB-CD3ζ) CAR, pCDCAR1 human X7X76 human scFv-ICOS-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0722-LX493 Anti-FOLH1 (X7X77) h(ICOS-4-1BB-CD3ζ) CAR, pCDCAR1 human X7X77 human scFv-ICOS-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0722-LX494 Anti-FOLH1 (X7X78) h(ICOS-4-1BB-CD3ζ) CAR, pCDCAR1 human X7X78 human scFv-ICOS-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0722-LX554 Anti-FOLH1 (X7X138) h(ICOS-4-1BB-CD3ζ) CAR, pCDCAR1 human X7X138 human scFv-ICOS-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0722-LX555 Anti-FOLH1 (X7X139) h(ICOS-4-1BB-CD3ζ) CAR, pCDCAR1 human X7X139 human scFv-ICOS-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0722-LX556 Anti-FOLH1 (X7X140) h(ICOS-4-1BB-CD3ζ) CAR, pCDCAR1 human X7X140 human scFv-ICOS-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0722-LX557 Anti-FOLH1 (X7X141) h(ICOS-4-1BB-CD3ζ) CAR, pCDCAR1 human X7X141 human scFv-ICOS-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0722-LX558 Anti-FOLH1 (X7X142) h(ICOS-4-1BB-CD3ζ) CAR, pCDCAR1 human X7X142 human scFv-ICOS-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0722-LX688 Anti-FOLH1 (XG1-077) h(CD28-41BB-CD3ζ) CAR, pMMLV human XG1-077 Mouse scFv-CD28-41BB-CD3ζ Recombinant Moloney murine leukemia virus (MMLV) retroviral vector T cell   Add to Cart   Datasheet
XS-0722-LX689 Anti-FOLH1 (X7X65) h(CD28-41BB-CD3ζ) CAR, pMMLV human X7X65 Mouse scFv-CD28-41BB-CD3ζ Recombinant Moloney murine leukemia virus (MMLV) retroviral vector T cell   Add to Cart   Datasheet
XS-0722-LX690 Anti-FOLH1 (X7X66) h(CD28-41BB-CD3ζ) CAR, pMMLV human X7X66 Mouse scFv-CD28-41BB-CD3ζ Recombinant Moloney murine leukemia virus (MMLV) retroviral vector T cell   Add to Cart   Datasheet
XS-0722-LX740 Anti-FOLH1 (X7X116) h(CD28-41BB-CD3ζ) CAR, pMMLV human X7X116 Humanized scFv-CD28-41BB-CD3ζ Recombinant Moloney murine leukemia virus (MMLV) retroviral vector T cell   Add to Cart   Datasheet
XS-0722-LX741 Anti-FOLH1 (X7X117) h(CD28-41BB-CD3ζ) CAR, pMMLV human X7X117 Humanized scFv-CD28-41BB-CD3ζ Recombinant Moloney murine leukemia virus (MMLV) retroviral vector T cell   Add to Cart   Datasheet
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