FOLH1

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This gene encodes a type II transmembrane glycoprotein belonging to the M28 peptidase family. The protein acts as a glutamate carboxypeptidase on different alternative substrates, including the nutrient folate and the neuropeptide N-acetyl-l-aspartyl-l-glutamate and is expressed in a number of tissues such as prostate, central and peripheral nervous system and kidney. A mutation in this gene may be associated with impaired intestinal absorption of dietary folates, resulting in low blood folate levels and consequent hyperhomocysteinemia. Expression of this protein in the brain may be involved in a number of pathological conditions associated with glutamate excitotoxicity. In the prostate the protein is up-regulated in cancerous cells and is used as an effective diagnostic and prognostic indicator of prostate cancer. This gene likely arose from a duplication event of a nearby chromosomal region. Alternative splicing gives rise to multiple transcript variants encoding several different isoforms.
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CAT Product Name Target Species Antibody Clone Antibody Host Receptor Construction Vector Type Targeting Cell Type CAR Vector Type Inquiry & Datasheet
XS-0722-LX61 Anti-FOLH1 (XG1-026) h(CD28-41BB-CD3ζ) CAR, pSBCAR1 human XG1-026 Mouse scFv-CD28-41BB-CD3ζ Sleeping Beauty (SB) transposon T cell   Add to Cart   Datasheet
XS-0722-LX62 Anti-FOLH1 (XG1-051) h(CD28-41BB-CD3ζ) CAR, pSBCAR1 human XG1-051 Mouse scFv-CD28-41BB-CD3ζ Sleeping Beauty (SB) transposon T cell   Add to Cart   Datasheet
XS-0722-LX63 Anti-FOLH1 (XG1-061) h(CD28-41BB-CD3ζ) CAR, pSBCAR1 human XG1-061 Mouse scFv-CD28-41BB-CD3ζ Sleeping Beauty (SB) transposon T cell   Add to Cart   Datasheet
XS-0722-LX64 Anti-FOLH1 (XG1-077) h(CD28-41BB-CD3ζ) CAR, pSBCAR1 human XG1-077 Mouse scFv-CD28-41BB-CD3ζ Sleeping Beauty (SB) transposon T cell   Add to Cart   Datasheet
XS-0722-LX84 Anti-FOLH1 (X7X84) h(CD28-41BB-CD3ζ) CAR, pSBCAR1 human X7X84 Humanized scFv-CD28-41BB-CD3ζ Sleeping Beauty (SB) transposon T cell   Add to Cart   Datasheet
XS-0722-LX85 Anti-FOLH1 (X7X85) h(CD28-41BB-CD3ζ) CAR, pSBCAR1 human X7X85 Humanized scFv-CD28-41BB-CD3ζ Sleeping Beauty (SB) transposon T cell   Add to Cart   Datasheet
XS-0722-LX86 Anti-FOLH1 (X7X86) h(CD28-41BB-CD3ζ) CAR, pSBCAR1 human X7X86 Humanized scFv-CD28-41BB-CD3ζ Sleeping Beauty (SB) transposon T cell   Add to Cart   Datasheet
XS-0722-LX87 Anti-FOLH1 (X7X87) h(CD28-41BB-CD3ζ) CAR, pSBCAR1 human X7X87 Humanized scFv-CD28-41BB-CD3ζ Sleeping Beauty (SB) transposon T cell   Add to Cart   Datasheet
XS-0722-LX148 Anti-FOLH1 (X7X148) h(CD28-41BB-CD3ζ) CAR, pSBCAR1 human X7X148 Humanized scFv-CD28-41BB-CD3ζ Sleeping Beauty (SB) transposon T cell   Add to Cart   Datasheet
XS-0722-LX276 Anti-FOLH1 (X7X68) h(CD28-OX40-CD3ζ) CAR, pCDCAR1 human X7X68 humanized scFv-CD28-OX40-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0722-LX277 Anti-FOLH1 (X7X69) h(CD28-OX40-CD3ζ) CAR, pCDCAR1 human X7X69 human scFv-CD28-OX40-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0722-LX770 Anti-FOLH1 (X7X146) h(CD28-41BB-CD3ζ) CAR, pMMLV human X7X146 Humanized scFv-CD28-41BB-CD3ζ Recombinant Moloney murine leukemia virus (MMLV) retroviral vector T cell   Add to Cart   Datasheet
XS-0722-LX771 Anti-FOLH1 (X7X147) h(CD28-41BB-CD3ζ) CAR, pMMLV human X7X147 Humanized scFv-CD28-41BB-CD3ζ Recombinant Moloney murine leukemia virus (MMLV) retroviral vector T cell   Add to Cart   Datasheet
XS-0722-LX772 Anti-FOLH1 (X7X148) h(CD28-41BB-CD3ζ) CAR, pMMLV human X7X148 Humanized scFv-CD28-41BB-CD3ζ Recombinant Moloney murine leukemia virus (MMLV) retroviral vector T cell   Add to Cart   Datasheet
XS-0722-LX773 Anti-FOLH1 (X7X149) h(CD28-41BB-CD3ζ) CAR, pMMLV human X7X149 mouse scFv-CD28-41BB-CD3ζ Recombinant Moloney murine leukemia virus (MMLV) retroviral vector T cell   Add to Cart   Datasheet
XS-0722-LX774 Anti-FOLH1 (X7X150) h(CD28-41BB-CD3ζ) CAR, pMMLV human X7X150 mouse scFv-CD28-41BB-CD3ζ Recombinant Moloney murine leukemia virus (MMLV) retroviral vector T cell   Add to Cart   Datasheet
XS-0722-LX775 Anti-FOLH1 (X7X151) h(CD28-41BB-CD3ζ) CAR, pMMLV human X7X151 mouse scFv-CD28-41BB-CD3ζ Recombinant Moloney murine leukemia virus (MMLV) retroviral vector T cell   Add to Cart   Datasheet
XS-0722-LX776 Anti-FOLH1 (X7X152) h(CD28-41BB-CD3ζ) CAR, pMMLV human X7X152 mouse scFv-CD28-41BB-CD3ζ Recombinant Moloney murine leukemia virus (MMLV) retroviral vector T cell   Add to Cart   Datasheet
XS-0722-LX777 Anti-FOLH1 (X7X153) h(CD28-41BB-CD3ζ) CAR, pMMLV human X7X153 mouse scFv-CD28-41BB-CD3ζ Recombinant Moloney murine leukemia virus (MMLV) retroviral vector T cell   Add to Cart   Datasheet
XS-0722-LX778 Anti-FOLH1 (X7X154) h(CD28-41BB-CD3ζ) CAR, pMMLV human X7X154 human scFv-CD28-41BB-CD3ζ Recombinant Moloney murine leukemia virus (MMLV) retroviral vector T cell   Add to Cart   Datasheet
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