FOLH1

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This gene encodes a type II transmembrane glycoprotein belonging to the M28 peptidase family. The protein acts as a glutamate carboxypeptidase on different alternative substrates, including the nutrient folate and the neuropeptide N-acetyl-l-aspartyl-l-glutamate and is expressed in a number of tissues such as prostate, central and peripheral nervous system and kidney. A mutation in this gene may be associated with impaired intestinal absorption of dietary folates, resulting in low blood folate levels and consequent hyperhomocysteinemia. Expression of this protein in the brain may be involved in a number of pathological conditions associated with glutamate excitotoxicity. In the prostate the protein is up-regulated in cancerous cells and is used as an effective diagnostic and prognostic indicator of prostate cancer. This gene likely arose from a duplication event of a nearby chromosomal region. Alternative splicing gives rise to multiple transcript variants encoding several different isoforms.
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CAT Product Name Target Species Antibody Clone Antibody Host Receptor Construction Vector Type Targeting Cell Type CAR Vector Type Inquiry & Datasheet
XS-0722-LX61 Anti-FOLH1 (XG1-026) h(CD28-41BB-CD3ζ) CAR, pSBCAR1 human XG1-026 Mouse scFv-CD28-41BB-CD3ζ Sleeping Beauty (SB) transposon T cell   Add to Cart   Datasheet
XS-0722-LX63 Anti-FOLH1 (XG1-061) h(CD28-41BB-CD3ζ) CAR, pSBCAR1 human XG1-061 Mouse scFv-CD28-41BB-CD3ζ Sleeping Beauty (SB) transposon T cell   Add to Cart   Datasheet
XS-0722-LX64 Anti-FOLH1 (XG1-077) h(CD28-41BB-CD3ζ) CAR, pSBCAR1 human XG1-077 Mouse scFv-CD28-41BB-CD3ζ Sleeping Beauty (SB) transposon T cell   Add to Cart   Datasheet
XS-0722-LX65 Anti-FOLH1 (X7X65) h(CD28-41BB-CD3ζ) CAR, pSBCAR1 human X7X65 Mouse scFv-CD28-41BB-CD3ζ Sleeping Beauty (SB) transposon T cell   Add to Cart   Datasheet
XS-0722-LX109 Anti-FOLH1 (X7X109) h(CD28-41BB-CD3ζ) CAR, pSBCAR1 human X7X109 Humanized scFv-CD28-41BB-CD3ζ Sleeping Beauty (SB) transposon T cell   Add to Cart   Datasheet
XS-0722-LX110 Anti-FOLH1 (X7X110) h(CD28-41BB-CD3ζ) CAR, pSBCAR1 human X7X110 Humanized scFv-CD28-41BB-CD3ζ Sleeping Beauty (SB) transposon T cell   Add to Cart   Datasheet
XS-0722-LX272 Anti-FOLH1 (XG1-077) h(CD28-OX40-CD3ζ) CAR, pCDCAR1 human XG1-077 Mouse scFv-CD28-OX40-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0722-LX273 Anti-FOLH1 (X7X65) h(CD28-OX40-CD3ζ) CAR, pCDCAR1 human X7X65 Mouse scFv-CD28-OX40-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0722-LX274 Anti-FOLH1 (X7X66) h(CD28-OX40-CD3ζ) CAR, pCDCAR1 human X7X66 Mouse scFv-CD28-OX40-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0722-LX275 Anti-FOLH1 (X7X67) h(CD28-OX40-CD3ζ) CAR, pCDCAR1 human X7X67 Mouse scFv-CD28-OX40-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0722-LX295 Anti-FOLH1 (X7X87) h(CD28-OX40-CD3ζ) CAR, pCDCAR1 human X7X87 Humanized scFv-CD28-OX40-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0722-LX296 Anti-FOLH1 (X7X88) h(CD28-OX40-CD3ζ) CAR, pCDCAR1 human X7X88 Humanized scFv-CD28-OX40-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0722-LX297 Anti-FOLH1 (X7X89) h(CD28-OX40-CD3ζ) CAR, pCDCAR1 human X7X89 Humanized scFv-CD28-OX40-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0722-LX360 Anti-FOLH1 (X7X152) h(CD28-OX40-CD3ζ) CAR, pCDCAR1 human X7X152 mouse scFv-CD28-OX40-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0722-LX361 Anti-FOLH1 (X7X153) h(CD28-OX40-CD3ζ) CAR, pCDCAR1 human X7X153 mouse scFv-CD28-OX40-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0722-LX478 Anti-FOLH1 (XG1-051) h(ICOS-4-1BB-CD3ζ) CAR, pCDCAR1 human XG1-051 Mouse scFv-ICOS-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0722-LX479 Anti-FOLH1 (XG1-061) h(ICOS-4-1BB-CD3ζ) CAR, pCDCAR1 human XG1-061 Mouse scFv-ICOS-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0722-LX480 Anti-FOLH1 (XG1-077) h(ICOS-4-1BB-CD3ζ) CAR, pCDCAR1 human XG1-077 Mouse scFv-ICOS-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0722-LX481 Anti-FOLH1 (X7X65) h(ICOS-4-1BB-CD3ζ) CAR, pCDCAR1 human X7X65 Mouse scFv-ICOS-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0722-LX482 Anti-FOLH1 (X7X66) h(ICOS-4-1BB-CD3ζ) CAR, pCDCAR1 human X7X66 Mouse scFv-ICOS-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
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