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GPI

All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

Glycosylphosphatidylinositol, or glycophosphatidylinositol, or GPI in short, is a phosphoglyceride that can be attached to the C-terminus of a protein during posttranslational modification. Proteins containing a GPI anchor play key roles in a wide variety of biological processes. It is composed of a phosphatidylinositol group linked through a carbohydrate-containing linker (glucosamine and mannose glycosidically bound to the inositol residue) and via an ethanolamine phosphate (EtNP) bridge to the C-terminal amino acid of a mature protein. The two fatty acids within the hydrophobic phosphatidyl-inositol group anchor the protein to the cell membrane.
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CAT Product Name Target Species Antibody Clone Antibody Host Receptor Construction Vector Type Targeting Cell Type CAR Vector Type Inquiry & Datasheet
XS-1222-ZP711 GPI (AMFR Receptor) h(CD28-CD3ζ) Ligand-based CAR, pCDCAR1 Human GPI-CD28-CD6ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-1222-ZP2111 GPI (AMFR Receptor) h(41BB-CD3ζ) Ligand-based CAR, pCDCAR1 Human GPI-41BB-CD6ζ Lentiviral vector T cell   Add to Cart   Datasheet
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