HIV-1 Nef

All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

The HIV Nef protein is a multifunctional virulence factor that perturbs intracellular membranes and signalling and is secreted into exosomes. While Nef-containing exosomes have a distinct proteomic profile, no comprehensive analysis of their miRNA cargo has been carried out. Since Nef functions as a viral suppressor of RNA interference and disturbs the distribution of RNA-induced silencing complex proteins between cells and exosomes, we hypothesized that it might also affect the export of miRNAs into exosomes.
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CAT Product Name Target Species TCR Clone Host Species Epitope Allele Vector Type Inquiry & Datasheet
XS-0623-LX30 Anti-HIV-1 nef (PD1/28-27-14 TCR) T cell receptor, pCDTCR1 Vector Human 27-14 Human Nef134-10 HLA-A*2402 Lentiviral vector   Add to Cart   Datasheet
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