IGF1R

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This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
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CAT Product Name Target Species Antibody Clone Antibody Host Receptor Construction Vector Type Targeting Cell Type CAR Vector Type Inquiry & Datasheet
CAR-ZP7896 Anti-IGF1R (Ganitumab) h(CD28-CD3ζ) CAR, pCDCAR1 Human Ganitumab Human scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP7897 Anti-IGF1R (Ganitumab) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human Ganitumab Human scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP7898 Anti-IGF1R (Dalotuzumab) h(CD28-CD3ζ) CAR, pCDCAR1 Human Dalotuzumab Human scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP7899 Anti-IGF1R (Dalotuzumab) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human Dalotuzumab Human scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP7900 Anti-IGF1R (AVE1642) h(CD28-CD3ζ) CAR, pCDCAR1 Human AVE1642 Humanized scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP7901 Anti-IGF1R (AVE1642) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human AVE1642 Humanized scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP7902 Anti-IGF1R (M57) h(CD28-CD3ζ) CAR, pCDCAR1 Human M57 Human scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP7903 Anti-IGF1R (M57) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human M57 Human scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP7904 Anti-IGF1R (GFA1) h(CD28-CD3ζ) CAR, pCDCAR1 Human GFA1 Human scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP7905 Anti-IGF1R (GFA1) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human GFA1 Human scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP7906 Anti-IGF1R (12D5) h(CD28-CD3ζ) CAR, pCDCAR1 Human 12D5 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP7907 Anti-IGF1R (12D5) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human 12D5 Mouse scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP7908 Anti-IGF1R (I-3466) h(CD28-CD3ζ) CAR, pCDCAR1 Human I-3466 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP7909 Anti-IGF1R (I-3466) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human I-3466 Mouse scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP7910 Anti-IGF1R (HI3466) h(CD28-CD3ζ) CAR, pCDCAR1 Human HI3466 Human scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP7911 Anti-IGF1R (HI3466) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human HI3466 Human scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP7912 Anti-IGF1R (GFA3) h(CD28-CD3ζ) CAR, pCDCAR1 Human GFA3 Human scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP7913 Anti-IGF1R (GFA3) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human GFA3 Human scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP7914 Anti-IGF1R (GFA5) h(CD28-CD3ζ) CAR, pCDCAR1 Human GFA5 Human scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP7915 Anti-IGF1R (GFA5) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human GFA5 Human scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
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