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ITGAL

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ITGAL encodes the integrin alpha L chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form the integrin lymphocyte function-associated antigen-1 (LFA-1), which is expressed on all leukocytes. LFA-1 plays a central role in leukocyte intercellular adhesion through interactions with its ligands, ICAMs 1-3 (intercellular adhesion molecules 1 through 3), and also functions in lymphocyte costimulatory signaling. Two transcript variants encoding different isoforms have been found for this gene.
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CAT Product Name Target Species Antibody Clone Antibody Host Receptor Construction Vector Type Targeting Cell Type CAR Vector Type Inquiry & Datasheet
CAR-YC0001 Anti-ITGAL (MHM.24) h(scFv-41BB-CD3ζ) CAR, pCDCAR1 Human MHM.24 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-YC0901 Anti-ITGAL (MHM.24) h(scFv-CD28-CD3ζ) CAR, pCDCAR1 Human MHM.24 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ1442 Anti-ITGAL (hu1124 (Efalizumab)) h(41BB-CD3ζ) CAR, pCDCAR1 Human hu1124 (Efalizumab) Rabbit scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ1443 Anti-ITGAL (S6F1) h(41BB-CD3ζ) CAR, pCDCAR1 Human S6F1 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ1444 Anti-ITGAL (chMHM24) h(41BB-CD3ζ) CAR, pCDCAR1 Human chMHM24 Chimeric scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ1445 Anti-ITGAL (huMHM24) h(41BB-CD3ζ) CAR, pCDCAR1 Human huMHM24 Humanized (mouse/human) scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ1446 Anti-ITGAL (2D7) h(41BB-CD3ζ) CAR, pCDCAR1 Mouse 2D7 Rat scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ1447 Anti-ITGAL (AL-57) h(41BB-CD3ζ) CAR, pCDCAR1 Human AL-57 Human scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ1448 Anti-ITGAL (Chimeric S6F1) h(41BB-CD3ζ) CAR, pCDCAR1 Human Chimeric S6F1 Chimeric scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ1449 Anti-ITGAL (MHM24) h(41BB-CD3ζ) CAR, pCDCAR1 Human MHM24 Human scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ1450 Anti-ITGAL (MEM-83) h(41BB-CD3ζ) CAR, pCDCAR1 Human MEM-83 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ4866 Anti-ITGAL (hu1124 (Efalizumab)) h(CD28-CD3ζ) CAR, pCDCAR1 Human hu1124 (Efalizumab) Rabbit scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ4867 Anti-ITGAL (S6F1) h(CD28-CD3ζ) CAR, pCDCAR1 Human S6F1 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ4868 Anti-ITGAL (chMHM24) h(CD28-CD3ζ) CAR, pCDCAR1 Human chMHM24 Chimeric scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ4869 Anti-ITGAL (huMHM24) h(CD28-CD3ζ) CAR, pCDCAR1 Human huMHM24 Humanized (mouse/human) scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ4870 Anti-ITGAL (2D7) h(CD28-CD3ζ) CAR, pCDCAR1 Mouse 2D7 Rat scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ4871 Anti-ITGAL (AL-57) h(CD28-CD3ζ) CAR, pCDCAR1 Human AL-57 Human scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ4872 Anti-ITGAL (Chimeric S6F1) h(CD28-CD3ζ) CAR, pCDCAR1 Human Chimeric S6F1 Chimeric scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ4873 Anti-ITGAL (MHM24) h(CD28-CD3ζ) CAR, pCDCAR1 Human MHM24 Human scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ4874 Anti-ITGAL (MEM-83) h(CD28-CD3ζ) CAR, pCDCAR1 Human MEM-83 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
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