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LCMVsSgp2

All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

Encapsidates the genome, protecting it from nucleases. The encapsidated genomic RNA is termed the nucleocapsid (NC). Serves as template for viral transcription and replication. The increased presence of protein N in host cell does not seem to trigger the switch from transcription to replication as observed in other negative strain RNA viruses. Through the interaction with host IKBKE, strongly inhibits the phosphorylation and nuclear translocation of host IRF3, a protein involved in interferon activation pathway, leading to the inhibition of interferon-beta and IRF3-dependent promoters activation. Encodes also a functional 3'-5' exoribonuclease that degrades preferentially dsRNA substrates and thereby participates in the suppression of interferon induction.
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CAT Product Name Target Species TCR Clone Host Species Epitope Allele Vector Type Inquiry & Datasheet
TCR-YC0629 Mouse anti-LCMVsSgp2 T cell receptor (YC33), pCDTCR1 LCMV YC33 Mouse YTAKYPNL H2-Kᵇ Lentiviral vector   Add to Cart   Datasheet
TCR-YC0630 Mouse anti-LCMVsSgp2 T cell receptor (YC34), pCDTCR1 LCMV YC34 Mouse YTVKYPNL H2-Kᵇ Lentiviral vector   Add to Cart   Datasheet
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