This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita.

Associated Disease
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CAT Product Name Target Species Antibody Clone Antibody Host Receptor Construction Vector Type Targeting Cell Type Inquiry & Datasheet
CAR-0120ZP1019 Anti-MAGE-A1 (HYB3) h(CD28-CD3ζ) CAR, pCDCAR1 Human HYB3 Human scFv-CD28-CD3ζ Lentiviral vector T Cell   Add to Cart   Datasheet
CAR-0120ZP1020 Anti-MAGE-A1 (HYB3) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human HYB3 Human scFv-4-1BB-CD3ζ Lentiviral vector T Cell   Add to Cart   Datasheet

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