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NOTCH1

All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

This gene encodes a member of the NOTCH family of proteins. Members of this Type I transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple different domain types. Notch signaling is an evolutionarily conserved intercellular signaling pathway that regulates interactions between physically adjacent cells through binding of Notch family receptors to their cognate ligands. The encoded preproprotein is proteolytically processed in the trans-Golgi network to generate two polypeptide chains that heterodimerize to form the mature cell-surface receptor. This receptor plays a role in the development of numerous cell and tissue types. Mutations in this gene are associated with aortic valve disease, Adams-Oliver syndrome, T-cell acute lymphoblastic leukemia, chronic lymphocytic leukemia, and head and neck squamous cell carcinoma.
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CAT Product Name Target Species Antibody Clone Antibody Host Receptor Construction Vector Type Targeting Cell Type CAR Vector Type Inquiry & Datasheet
CAR-WFY1570 Anti-NOTCH1 (CBFYH-2677) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBFYH-2677 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY1571 Anti-NOTCH1 (CBFYH-2678) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBFYH-2678 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY1572 Anti-NOTCH1 (CBFYH-2679) h(41BB-CD3ζ) CAR, pCDCAR1 Mouse, Rat, Human CBFYH-2679 Rabbit scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY1573 Anti-NOTCH1 (CBFYH-2680) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBFYH-2680 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY1574 Anti-NOTCH1 (CBFYH-2681) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBFYH-2681 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY4823 Anti-NOTCH1 (CBFYH-2677) h(CD28-CD3ζ) CAR, pCDCAR1 Human CBFYH-2677 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY4824 Anti-NOTCH1 (CBFYH-2678) h(CD28-CD3ζ) CAR, pCDCAR1 Human CBFYH-2678 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY4825 Anti-NOTCH1 (CBFYH-2679) h(CD28-CD3ζ) CAR, pCDCAR1 Mouse, Rat, Human CBFYH-2679 Rabbit scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY4826 Anti-NOTCH1 (CBFYH-2680) h(CD28-CD3ζ) CAR, pCDCAR1 Human CBFYH-2680 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WFY4827 Anti-NOTCH1 (CBFYH-2681) h(CD28-CD3ζ) CAR, pCDCAR1 Human CBFYH-2681 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-LY060 Anti-NOTCH1 h(41BB-CD3ζ) CAR, pCDCAR1 Canine, Human, Mouse Rat scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-LY1700 Anti-NOTCH1 h(CD28-CD3ζ) CAR, pCDCAR1 Canine, Human, Mouse Rat scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WJ1542 Anti-NOTCH1 (N248A) h(41BB-CD3ζ) CAR, pCDCAR1 Human N248A Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WJ1543 Anti-NOTCH1 (A12.2) h(41BB-CD3ζ) CAR, pCDCAR1 Human A12.2 Human scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WJ1544 Anti-NOTCH1 (hN1S3-67) h(41BB-CD3ζ) CAR, pCDCAR1 Human hN1S3-67 Human scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WJ1545 Anti-NOTCH1 (23814) h(41BB-CD3ζ) CAR, pCDCAR1 Human 23814 Human scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WJ1578 Anti-NOTCH1 (C44H11) h(41BB-CD3ζ) CAR, pCDCAR1 C44H11 Rabbit scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WJ1579 Anti-NOTCH1 (D1E11) h(41BB-CD3ζ) CAR, pCDCAR1 D1E11 Rabbit scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WJ1580 Anti-NOTCH1 (D3B8) h(41BB-CD3ζ) CAR, pCDCAR1 D3B8 Rabbit scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-WJ1581 Anti-NOTCH1 (D6F11) h(41BB-CD3ζ) CAR, pCDCAR1 D6F11 Rabbit scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
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