NS5A

HCV is a positive, single-stranded RNA virus in the Flaviviridae family. The genome is approximately 10,000 nucleotides and encodes a single polyprotein of about 3,000 amino acids. HCV has four structural proteins (C, E1, E2 and p7) and six nonstructural (NS) proteins (NS2, NS3, NS4A, NS4B, NS5A, and NS5B). NS5A is a hydrophilic phosphoprotein which plays an important role in viral replication, modulation of cell signaling pathways and the interferon response. It is known to bind to endoplasmic reticulum anchored human VAP proteins.

Associated Disease
  • HCV infection

TCR Vector Products Product list:

Catalog Target Target
Species
Antibody
Clone
scFv-Host
Animal
Vector
length
Vector
Type
Epitope Format HLA Data
sheet
Price
TCR-C185Z NS5A HCV 19 Mouse ~8kb Lentiviral VLTDFKTWL Codon optimized HLA-A2 Inquiry
TCR-C186Z NS5A HCV 69 Mouse ~8kb Lentiviral VLTDFKTWL Codon optimized HLA-A2 Inquiry

TCR Viral Particles Product list:

Catalog Target
Species
Antibody
Clone
scFv-Host
Animal
Packaging
System
Epitope Format Titer Data
sheet
Price
VP-TCR-C353 HCV 19 Mouse Lentivirus VLTDFKTWL Codon optimized TCR > 10⁷ IFU/ml Inquiry
VP-TCR-C354 HCV 69 Mouse Lentivirus VLTDFKTWL Codon optimized TCR > 10⁷ IFU/ml Inquiry
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