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OGDH

All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

This gene encodes one subunit of the 2-oxoglutarate dehydrogenase complex. This complex catalyzes the overall conversion of 2-oxoglutarate (alpha-ketoglutarate) to succinyl-CoA and CO(2) during the Krebs cycle. The protein is located in the mitochondrial matrix and uses thiamine pyrophosphate as a cofactor. A congenital deficiency in 2-oxoglutarate dehydrogenase activity is believed to lead to hypotonia, metabolic acidosis, and hyperlactatemia. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
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CAT Product Name Target Species Antibody Clone Antibody Host Receptor Construction Vector Type Targeting Cell Type CAR Vector Type Inquiry & Datasheet
CAR-CQ1668 Anti-OGDH (9F4BD5) h(41BB-CD3ζ) CAR, pCDCAR1 Human 9F4BD5 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ1669 Anti-OGDH (CBXO-0405) h(41BB-CD3ζ) CAR, pCDCAR1 Human, Rat CBXO-0405 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ5092 Anti-OGDH (9F4BD5) h(CD28-CD3ζ) CAR, pCDCAR1 Human 9F4BD5 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CQ5093 Anti-OGDH (CBXO-0405) h(CD28-CD3ζ) CAR, pCDCAR1 Human, Rat CBXO-0405 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
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