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PB1-F2

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Plays an important role in promoting lung pathology in both primary viral infection and secondary bacterial infection. Promotes alteration of mitochondrial morphology, dissipation of mitochondrial membrane potential, and cell death. Alternatively, inhibits the production of interferon in the infected cell at the level of host mitochondrial antiviral signaling MAVS. Its level of expression differs greatly depending on which cell type is infected, in a manner that is independent of the levels of expression of other viral proteins. Monocytic cells are more affected than epithelial cells. Seems to disable virus-infected monocytes or other host innate immune cells. During early stage of infection, predisposes the mitochondria to permeability transition through interaction with host SLC25A6/ANT3 and VDAC1. These proteins participate in the formation of the permeability transition pore complex (PTPC) responsible of the release of mitochondrial products that triggers apoptosis.
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CAT Product Name Target Species TCR Clone Host Species Epitope Allele Vector Type Inquiry & Datasheet
TCR-YC0842 Mouse anti-PB1-F2 T cell receptor (903), pCDTCR1 IAV 903 Mouse LSLRNPILV H2-Dᵇ Lentiviral vector   Add to Cart   Datasheet
TCR-YC0843 Mouse anti-PB1-F2 T cell receptor (943), pCDTCR1 IAV 943 Mouse LSLRNPILV H2-Dᵇ Lentiviral vector   Add to Cart   Datasheet
TCR-YC0844 Mouse anti-PB1-F2 T cell receptor (1001), pCDTCR1 IAV 1001 Mouse LSLRNPILV H2-Dᵇ Lentiviral vector   Add to Cart   Datasheet
TCR-YC0845 Mouse anti-PB1-F2 T cell receptor (1232), pCDTCR1 IAV 1232 Mouse LSLRNPILV H2-Dᵇ Lentiviral vector   Add to Cart   Datasheet
TCR-YC0846 Mouse anti-PB1-F2 T cell receptor (1257), pCDTCR1 IAV 1257 Mouse LSLRNPILV H2-Dᵇ Lentiviral vector   Add to Cart   Datasheet
TCR-YC0850 Mouse anti-PB1-F2 T cell receptor (1825), pCDTCR1 IAV 1825 Mouse LSLRNPILV H2-Dᵇ Lentiviral vector   Add to Cart   Datasheet
TCR-YC0851 Mouse anti-PB1-F2 T cell receptor (1920), pCDTCR1 IAV 1920 Mouse LSLRNPILV H2-Dᵇ Lentiviral vector   Add to Cart   Datasheet
TCR-YC0852 Mouse anti-PB1-F2 T cell receptor (2014), pCDTCR1 IAV 2014 Mouse LSLRNPILV H2-Dᵇ Lentiviral vector   Add to Cart   Datasheet
TCR-YC0853 Mouse anti-PB1-F2 T cell receptor (2323), pCDTCR1 IAV 2323 Mouse LSLRNPILV H2-Dᵇ Lentiviral vector   Add to Cart   Datasheet
TCR-YC0854 Mouse anti-PB1-F2 T cell receptor (2421), pCDTCR1 IAV 2421 Mouse LSLRNPILV H2-Dᵇ Lentiviral vector   Add to Cart   Datasheet
TCR-YC0855 Mouse anti-PB1-F2 T cell receptor (2557), pCDTCR1 IAV 2557 Mouse LSLRNPILV H2-Dᵇ Lentiviral vector   Add to Cart   Datasheet
TCR-YC0856 Mouse anti-PB1-F2 T cell receptor (2821), pCDTCR1 IAV 2821 Mouse LSLRNPILV H2-Dᵇ Lentiviral vector   Add to Cart   Datasheet
TCR-YC0857 Mouse anti-PB1-F2 T cell receptor (2930), pCDTCR1 IAV 2930 Mouse LSLRNPILV H2-Dᵇ Lentiviral vector   Add to Cart   Datasheet
TCR-YC0858 Mouse anti-PB1-F2 T cell receptor (3006), pCDTCR1 IAV 3006 Mouse LSLRNPILV H2-Dᵇ Lentiviral vector   Add to Cart   Datasheet
TCR-ZP069 Mouse anti-PB1-F2 T cell receptor (2891), pCDTCR1 Influenza A virus 2891 Mouse LSLRNPILV H2-Kb Lentiviral vector   Add to Cart   Datasheet
TCR-ZP071 Mouse anti-PB1-F2 T cell receptor (2931), pCDTCR1 Influenza A virus 2931 Mouse LSLRNPILV H2-Kb Lentiviral vector   Add to Cart   Datasheet
TCR-ZP072 Mouse anti-PB1-F2 T cell receptor (2945), pCDTCR1 Influenza A virus 2945 Mouse LSLRNPILV H2-Kb Lentiviral vector   Add to Cart   Datasheet
TCR-ZP073 Mouse anti-PB1-F2 T cell receptor (2952), pCDTCR1 Influenza A virus 2952 Mouse LSLRNPILV H2-Kb Lentiviral vector   Add to Cart   Datasheet
TCR-ZP074 Mouse anti-PB1-F2 T cell receptor (2992), pCDTCR1 Influenza A virus 2992 Mouse LSLRNPILV H2-Kb Lentiviral vector   Add to Cart   Datasheet
TCR-ZP076 Mouse anti-PB1-F2 T cell receptor (3007), pCDTCR1 Influenza A virus 3007 Mouse LSLRNPILV H2-Kb Lentiviral vector   Add to Cart   Datasheet
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