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PRAME

All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

This gene encodes an antigen that is preferentially expressed in human melanomas and that is recognized by cytolytic T lymphocytes. It is not expressed in normal tissues, except testis. The encoded protein acts as a repressor of retinoic acid receptor, and likely confers a growth advantage to cancer cells via this function. Alternative splicing results in multiple transcript variants.
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CAT Product Name Target Species TCR Clone Host Species Epitope Allele Vector Type Inquiry & Datasheet
TCR-ZP005 Human anti-PRAME T cell receptor (CBL-Z005), pCDTCR1 Human CBL-Z005 Human VLDGLDVLL HLAA0202 Lentiviral vector   Add to Cart   Datasheet
TCR-ZP009 Human anti-PRAME T cell receptor (CBL-Z006), pCDTCR1 Human CBL-Z006 Human SLLQHLIGL HLA-A2 Lentiviral vector   Add to Cart   Datasheet
TCR-LA-ZP120 Anti-PRAME (ALYVDSLFFL) TCR-Like Antibody (Pr20), HLA-A*0201-Restricted Human Pr20 ALYVDSLFFL HLA-A*0201   Add to Cart   Datasheet
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