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QARS

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Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. In metazoans, 9 aminoacyl-tRNA synthetases specific for glutamine (gln), glutamic acid (glu), and 7 other amino acids are associated within a multienzyme complex. Although present in eukaryotes, glutaminyl-tRNA synthetase (QARS) is absent from many prokaryotes, mitochondria, and chloroplasts, in which Gln-tRNA(Gln) is formed by transamidation of the misacylated Glu-tRNA(Gln). Glutaminyl-tRNA synthetase belongs to the class-I aminoacyl-tRNA synthetase family. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013]
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CAT Product Name Target Species Antibody Clone Antibody Host Receptor Construction Vector Type Targeting Cell Type CAR Vector Type Inquiry & Datasheet
CAR-LY680 Anti-QARS (XR284) h(41BB-CD3ζ) CAR, pCDCAR1 Human XR284 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-LY681 Anti-QARS (CBLG1-1276) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBLG1-1276 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-LY2320 Anti-QARS(XR284) h(CD28-CD3ζ) CAR, pCDCAR1 Human XR284 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-LY2321 Anti-QARS(CBLG1-1276) h(CD28-CD3ζ) CAR, pCDCAR1 Human CBLG1-1276 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
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