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SSX2

The product of this gene belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneous humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. This gene, and also the SSX1 and SSX4 family members, have been involved in t(X;18)(p11.2;q11.2) translocations that are characteristically found in all synovial sarcomas. This translocation results in the fusion of the synovial sarcoma translocation gene on chromosome 18 to one of the SSX genes on chromosome X. The encoded hybrid proteins are likely responsible for transforming activity. Alternative splicing of this gene results in multiple transcript variants. This gene also has an identical duplicate, GeneID: 727837, located about 45 kb downstream in the opposite orientation on chromosome X.

Associated Disease
  • TCR Vector Products
  • TCR Viral Particles
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  • Antibody Host:
  • HLA:
  • Vector Type:
CAT Product Name Target SpeciesAntibody CloneAntibody HostEpitopeHLAVector Type Inquiry & Datasheet
TCR-L107 Murinized (from Human) anti-SSX2 (KASEKIFYV) T Cell Receptor, pMSGV1 Human Murinized (from Human) KASEKIFYV HLA-A2 retroviral vector   Inquiry
  Datasheet
TCR-C239Z Human anti-SSX2 T cell receptor (TCR5), pCDTCR1 Human TCR5 Human KASEKIFYV HLA-A*0201 Lentiviral   Inquiry
  Datasheet
TCR-L262 Human anti-SSX-2 T cell receptor, pCDTCR1 Human Human KASEKIFYV HLA-A2 Lentiviral   Inquiry
  Datasheet
TCR-L263 Human anti-SSX-2 T cell receptor, pCDTCR1 Human Human KASEKIFYV HLA-A2 Lentiviral   Inquiry
  Datasheet
TCR-C240Z Murinized anti-SSX2 T cell receptor (TCR5), pCDTCR1 Human TCR5 Murinized KASEKIFYV HLA-A*0201 Lentiviral   Inquiry
  Datasheet
TCR-L106Z Murinized anti-SSX2 (aa41-49) T cell receptor, pCDTCR1 Human Murinized (from Human) KASEKIFYV HLA-A2 Lentiviral   Inquiry
  Datasheet

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