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TBL1XR1

All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

TBL1XR1 is a member of the WD40 repeat-containing gene family and shares sequence similarity with transducin (beta)-like 1X-linked (TBL1X). TBL1XR1 is thought to be a component of both nuclear receptor corepressor (N-CoR) and histone deacetylase 3 (HDAC 3) complexes, and is required for transcriptional activation by a variety of transcription factors. Mutations in these gene have been associated with some autism spectrum disorders, and one finding suggests that haploinsufficiency of this gene may be a cause of intellectual disability with dysmorphism. Mutations in TBL1XR1 as well as recurrent translocations involving this gene have also been observed in some tumors.
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CAT Product Name Target Species Antibody Clone Antibody Host Receptor Construction Vector Type Targeting Cell Type CAR Vector Type Inquiry & Datasheet
CAR-YJ223 Anti-TBL1XR1 (3G7) h(41BB-CD3ζ) CAR, pCDCAR1 Human 3G7 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-YJ224 Anti-TBL1XR1 (4F3-A8-D9) h(41BB-CD3ζ) CAR, pCDCAR1 Human, Mouse 4F3-A8-D9 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-YJ723 Anti-TBL1XR1 (3G7) h(CD28-CD3ζ) CAR, pCDCAR1 Human 3G7 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-YJ724 Anti-TBL1XR1 (4F3-A8-D9) h(CD28-CD3ζ) CAR, pCDCAR1 Human, Mouse 4F3-A8-D9 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
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