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TIM3

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The protein encoded by this gene belongs to the immunoglobulin superfamily, and TIM family of proteins. CD4-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas, Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. This protein is a Th1-specific cell surface protein that regulates macrophage activation, and inhibits Th1-mediated auto- and alloimmune responses, and promotes immunological tolerance.
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CAT Product Name Target Species Antibody Clone Antibody Host Receptor Construction Vector Type Targeting Cell Type CAR Vector Type Inquiry & Datasheet
CAR-YF169 Anti-TIM3 (CBL-YF055) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human CBL-YF055 Mouse scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-YF170 Anti-TIM3 (CBL-YF055) h(CD28-CD3ζ) CAR, pCDCAR1 Human CBL-YF055 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP094 Anti-TIM3 (IGHV812) h(41BB-CD3ζ) CAR, pCDCAR1 Human IGHV812 Mouse scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP095 Anti-TIM3 (IGHV812) h(CD28-CD3ζ) CAR, pCDCAR1 Human IGHV812 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-SB-LX0441 Anti-TIM3 (TSR-022) h(CD28-CD3ζ) CAR, pSBCAR1 Human TSR-022 Mouse scFv-CD28-CD3ζ Sleeping Beauty (SB) transposon T cell   Add to Cart   Datasheet
CAR-SB-LX0442 Anti-TIM3 (mAb15) h(CD28-CD3ζ) CAR, pSBCAR1 Human mAb15 Mouse scFv-CD28-CD3ζ Sleeping Beauty (SB) transposon T cell   Add to Cart   Datasheet
CAR-SB-LX0443 Anti-TIM3 (F38-2E2) h(CD28-CD3ζ) CAR, pSBCAR1 Human F38-2E2 Mouse scFv-CD28-CD3ζ Sleeping Beauty (SB) transposon T cell   Add to Cart   Datasheet
XS-0622-ZP3224 Anti-TIM3 h(VHH1-VHH2-CD28-CD3ζ) Biepitopic CAR, pCDCAR1 Human VHH1-VHH2-CD28-CD3ζ Lentiviral vector T Cell   Add to Cart   Datasheet
XS-0622-ZP3396 Anti-TIM3 h(VHH1-VHH2-4-1BB-CD3ζ) Biepitopic CAR, pCDCAR1 VHH1-VHH2-4-1BB-CD3ζ Lentiviral vector T Cell   Add to Cart   Datasheet
XS-0822-YF504 Anti-Human TIM3 (XW-504) h(41BB-CD3ζ) CAR IVT Plasmid, pCARIVT Human XW-504 Mouse scFv-41BB-CD3ζ In Vitro Transcription (IVT) Vector   Add to Cart   Datasheet
XS-0822-YF505 Anti-Human TIM3 (XW-505) h(41BB-CD3ζ) CAR IVT Plasmid, pCARIVT Human XW-505 Mouse scFv-41BB-CD3ζ In Vitro Transcription (IVT) Vector   Add to Cart   Datasheet
XS-0822-YF506 Anti-Human TIM3 (XW-506) h(41BB-CD3ζ) CAR IVT Plasmid, pCARIVT Human XW-506 Mouse scFv-41BB-CD3ζ In Vitro Transcription (IVT) Vector   Add to Cart   Datasheet
XS-1122-YF504 Anti-TIM3 KIR CAR (scFv-KIR2DS2-DAP12, XW-504), pCDCAR1 Human XW-504 Mouse scFv-KIR2DS2 TM&ICD-2A-DAP12 Lentiviral vector T Cell   Add to Cart   Datasheet
XS-1122-YF505 Anti-TIM3 KIR CAR (scFv-KIR2DS2-DAP12, XW-505), pCDCAR1 Human XW-505 Mouse scFv-KIR2DS2 TM&ICD-2A-DAP12 Lentiviral vector T Cell   Add to Cart   Datasheet
XS-1122-YF506 Anti-TIM3 KIR CAR (scFv-KIR2DS2-DAP12, XW-506), pCDCAR1 Human XW-506 Mouse scFv-KIR2DS2 TM&ICD-2A-DAP12 Lentiviral vector T Cell   Add to Cart   Datasheet
XS-1122-YF1424 Anti-TIM3 TCR-ABR (scFv-TCRα, XW-504) CAR Plasmid, pCDCAR1 Human XW-504 Mouse scFv-TCRα Lentiviral vector T Cell   Add to Cart   Datasheet
XS-1122-YF1425 Anti-TIM3 TCR-ABR (scFv-TCRα, XW-505) CAR Plasmid, pCDCAR1 Human XW-505 Mouse scFv-TCRα Lentiviral vector T Cell   Add to Cart   Datasheet
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