TNFRSF1B

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The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein and TNF-receptor 1 form a heterocomplex that mediates the recruitment of two anti-apoptotic proteins, c-IAP1 and c-IAP2, which possess E3 ubiquitin ligase activity. The function of IAPs in TNF-receptor signalling is unknown, however, c-IAP1 is thought to potentiate TNF-induced apoptosis by the ubiquitination and degradation of TNF-receptor-associated factor 2, which mediates anti-apoptotic signals. Knockout studies in mice also suggest a role of this protein in protecting neurons from apoptosis by stimulating antioxidative pathways.
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CAT Product Name Target Species Antibody Clone Antibody Host Receptor Construction Vector Type Targeting Cell Type CAR Vector Type Inquiry & Datasheet
CAR-ZP6303 Anti-TNFRSF1B (XHM535) h(CD28-CD3ζ) CAR, pCDCAR1 Human XHM535 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP6304 Anti-TNFRSF1B (XHM535) h(41BB-CD3ζ) CAR, pCDCAR1 Human XHM535 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP6305 Anti-TNFRSF1B (JM113-01) h(CD28-CD3ζ) CAR, pCDCAR1 Human JM113-01 Rabbit scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP6306 Anti-TNFRSF1B (JM113-01) h(41BB-CD3ζ) CAR, pCDCAR1 Human JM113-01 Rabbit scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP6316 Anti-TNFRSF1B (CBYJT-3816) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBYJT-3816 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP6317 Anti-TNFRSF1B (80M2) h(CD28-CD3ζ) CAR, pCDCAR1 Human 80M2 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP6318 Anti-TNFRSF1B (80M2) h(41BB-CD3ζ) CAR, pCDCAR1 Human 80M2 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP6319 Anti-TNFRSF1B (2/220) h(CD28-CD3ζ) CAR, pCDCAR1 Human 2/220 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP6320 Anti-TNFRSF1B (2/220) h(41BB-CD3ζ) CAR, pCDCAR1 Human 2/220 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP6321 Anti-TNFRSF1B (CBYJT-3815) h(CD28-CD3ζ) CAR, pCDCAR1 Human CBYJT-3815 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP6322 Anti-TNFRSF1B (CBYJT-3815) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBYJT-3815 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP6323 Anti-TNFRSF1B (3G7A02) h(CD28-CD3ζ) CAR, pCDCAR1 Human 3G7A02 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP6324 Anti-TNFRSF1B (3G7A02) h(41BB-CD3ζ) CAR, pCDCAR1 Human 3G7A02 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP6327 Anti-TNFRSF1B (HM102) h(CD28-CD3ζ) CAR, pCDCAR1 Human HM102 Rat scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP6328 Anti-TNFRSF1B (HM102) h(41BB-CD3ζ) CAR, pCDCAR1 Human HM102 Rat scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP6329 Anti-TNFRSF1B (TR75-54.7) h(CD28-CD3ζ) CAR, pCDCAR1 Human TR75-54.7 Hamster scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP6330 Anti-TNFRSF1B (TR75-54.7) h(41BB-CD3ζ) CAR, pCDCAR1 Human TR75-54.7 Hamster scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP6331 Anti-TNFRSF1B (TR75-32.4) h(CD28-CD3ζ) CAR, pCDCAR1 Human TR75-32.4 Hamster scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP6332 Anti-TNFRSF1B (TR75-32.4) h(41BB-CD3ζ) CAR, pCDCAR1 Human TR75-32.4 Hamster scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP6333 Anti-TNFRSF1B (TR75-54) h(CD28-CD3ζ) CAR, pCDCAR1 Human TR75-54 Hamster scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
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