TR1

TR1 is known as the death receptor (DR4), TRAIL receptor 1 (TRAILR1), and tumor necrosis factor receptor superfamily member 10A (TNFRSF10A), which belongs to the superfamily of TFN-receptor. TR1 is associated with chronic lymphocytic leukemia (CLL), mantle cell lymphoma (MCL), prostate cancer, bladder cancer, head and neck squamous-cell carcinoma (HNSCC), melanoma, renal carcinoma and ovarian carcinoma. TR1 transduces cell death signal and induce cell apoptosis through activated by tumor necrosis factor-related apoptosis inducing ligand.

Associated Disease

CAR Vector Products Product list:

Catalog Targeting
Cell Type
Generation Antibody
Clone
Vector
Length
Vector
Type
Vector Design Antibody
Host
Data
sheet
Price
CAR-MZ112 T cell First TR404 ~8kb Retroviral scFv-CD3ζ Human Inquiry
CAR-MZ113 T cell Second TR404 ~8kb Retroviral scFv-CD28-CD3ζ Human Inquiry
CAR-MZ114 T cell Second TR404 ~8kb Retroviral scFv-CD137-CD3ζ Human Inquiry
CAR-MZ115 T cell Third TR404 ~8kb Retroviral scFv-CD28-CD137-CD3ζ Human Inquiry
CAR-MZ242 T cell Third ~8kb Retroviral CD8-CD28-CD137-CD3ζ Human Inquiry

CAR Viral Particles Product list:

Catalog Antibody
Clone
Packaging
System
Generation Gene
Construct
Promotor Packaging
Cell
Titer Data
sheet
Price
VP-CAR-LC811 TR404 Lentivirus First scFv (TR404)-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC812 TR404 Lentivirus Second scFv (TR404)-CD28-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC813 TR404 Lentivirus Second scFv (TR404)-CD137-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
VP-CAR-LC814 TR404 Lentivirus Third scFv (TR404)-CD28-CD137-CD3ζ CMV 293T > 10⁷ IFU/ml Inquiry
CONTACT US

USA
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Tel: 1-631-871-5806
Fax: 1-631-207-8356
Email:

Europe
Ringstrasse 4, 64401 Gross-Bieberau, Germany
Tel: 44-207-097-1828

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