All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.
TR1 is known as the death receptor (DR4), TRAIL receptor 1 (TRAILR1), and tumor necrosis factor receptor superfamily member 10A (TNFRSF10A), which belongs to the superfamily of TFN-receptor. TR1 is associated with chronic lymphocytic leukemia (CLL), mantle cell lymphoma (MCL), prostate cancer, bladder cancer, head and neck squamous-cell carcinoma (HNSCC), melanoma, renal carcinoma and ovarian carcinoma. TR1 transduces cell death signal and induce cell apoptosis through activated by tumor necrosis factor-related apoptosis inducing ligand.
CAT | Product Name | Target Species | Antibody Clone | Antibody Host | Receptor Construction | Vector Type | Targeting Cell Type | CAR Vector Type | Inquiry & Datasheet |
CAR-MZ112 | Anti-TR1 (TR404) h(CD3ζ) CAR, pCDCAR1 | Human | TR404 | Human | scFv-CD3ζ | Retroviral | T cell | ||
CAR-MZ113 | Anti-TR1 (TR404) h(CD28-CD3ζ) CAR, pCDCAR1 | Human | TR404 | Human | scFv-CD28-CD3ζ | Retroviral | T cell | ||
CAR-MZ114 | Anti-TR1 (TR404) h(CD137-CD3ζ) CAR, pCDCAR1 | Human | TR404 | Human | scFv-CD137-CD3ζ | Retroviral | T cell | ||
CAR-MZ115 | Anti-TR1 (TR404) h(CD28-CD137-CD3ζ) CAR, pCDCAR1 | Human | TR404 | Human | scFv-CD28-CD137-CD3ζ | Retroviral | T cell | ||
CAR-MZ242 | Anti-TR1, CD8 h(CD28-CD137-CD3ζ) CAR, pCDCAR1 | Human | XHM543 | Human | CD8-CD28-CD137-CD3ζ | Retroviral | T cell |
The latest newsletter to introduce the latest breaking information, our site updates, field and other scientific news, important events, and insights from industry leaders
LEARN MORE NEWSLETTERCellRapeutics™ In Vivo Cell Engineering: One-stop in vivo T/B/NK cell and macrophage engineering services covering vectors construction to function verification.
LEARN MORE SOLUTIONSilence™ CAR-T Cell: A novel platform to enhance CAR-T cell immunotherapy by combining RNAi technology to suppress genes that may impede CAR functionality.
LEARN MORE NOVEL TECHNOLOGYCanine CAR-T Therapy Development: From early target discovery, CAR design and construction, cell culture, and transfection, to in vitro and in vivo function validation.
LEARN MORE SOLUTION