All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.
T-cell receptor beta constant 1 (TRBC1) is a protein that in humans is encoded by the TRBC1 gene. The α/β T-cell receptor (TCR) is a pan T-cell antigen, expressed on>90% of T-cell lymphomas and all normal T-cells. An overlooked feature of the TCR is that the β-constant region comprises 2 functionally identical genes: TRBC1 and TRBC2. Each T-cell expresses only one of these. Hence, normal T-cells will be a mixture of individual cells expressing either TRBC1 or 2, while a clonal T-cell cancer will express TRBC1 or 2 in its entirety.
CAT | Product Name | Target Species | Antibody Clone | Antibody Host | Receptor Construction | Vector Type | Targeting Cell Type | CAR Vector Type | Inquiry & Datasheet |
CAR-LC094 | Anti-TRBC1 (Jovi-1) h((CD8stk)-CD28-CD3ζ) CAR, pCDCAR1 | Human | Jovi-1 | Mouse | scFv-(CD8stk)-CD28-CD3ζ | Retroviral | T cell | ||
CAR-LC095 | Anti-TRBC1 (Jovi-1) h((CH2CH3pvaa)-CD28-CD3ζ) CAR, pCDCAR1 | Human | Jovi-1 | Mouse | scFv-(CH2CH3pvaa)-CD28-CD3ζ | Retroviral | T cell | ||
XS-0922-ZP907 | Anti-TRBC1 (CB-P26) h(CD28-CD3ζ) CAR, pCDCAR1 | Mouse | CB-P26 | Rat | scFv-CD28-CD3ζ | Lentiviral vector | T cell | ||
XS-0922-ZP1217 | Anti-TRBC1 (CB-P26) h(4-1BB-CD3ζ) CAR, pCDCAR1 | Mouse | CB-P26 | Rat | scFv-4-1BB-CD3ζ | Lentiviral vector | T cell | ||
XS-1122-YF898 | Anti-TRBC1 KIR CAR (scFv-KIR2DS2-DAP12, XW-898), pCDCAR1 | Human | XW-898 | Mouse | scFv-KIR2DS2 TM&ICD-2A-DAP12 | Lentiviral vector | T Cell | ||
XS-1122-YF899 | Anti-TRBC1 KIR CAR (scFv-KIR2DS2-DAP12, XW-899), pCDCAR1 | Mouse | XW-899 | Rat | scFv-KIR2DS2 TM&ICD-2A-DAP12 | Lentiviral vector | T Cell | ||
XS-1122-YF1818 | Anti-TRBC1 TCR-ABR (scFv-TCRα, XW-898) CAR Plasmid, pCDCAR1 | Human | XW-898 | Mouse | scFv-TCRα | Lentiviral vector | T Cell | ||
XS-1122-YF1819 | Anti-TRBC1 TCR-ABR (scFv-TCRα, XW-899) CAR Plasmid, pCDCAR1 | Mouse | XW-899 | Rat | scFv-TCRα | Lentiviral vector | T Cell | ||
XS-1122-YF2738 | Anti-TRBC1 TCR-ABR (scFv-TCRβ, XW-898) CAR Plasmid, pCDCAR1 | Human | XW-898 | Mouse | scFv-TCRβ | Lentiviral vector | T Cell | ||
XS-1122-YF2739 | Anti-TRBC1 TCR-ABR (scFv-TCRβ, XW-899) CAR Plasmid, pCDCAR1 | Mouse | XW-899 | Rat | scFv-TCRβ | Lentiviral vector | T Cell | ||
XS-1122-YF3658 | Anti-TRBC1 TCR-ABR (scFv-CD3γ, XW-898) CAR Plasmid, pCDCAR1 | Human | XW-898 | Mouse | scFv-CD3γ | Lentiviral vector | T Cell | ||
XS-1122-YF3659 | Anti-TRBC1 TCR-ABR (scFv-CD3γ, XW-899) CAR Plasmid, pCDCAR1 | Mouse | XW-899 | Rat | scFv-CD3γ | Lentiviral vector | T Cell | ||
XS-1122-YF5498 | Anti-TRBC1 TCR-ABR (scFv-CD3ε, XW-898) CAR Plasmid, pCDCAR1 | Human | XW-898 | Mouse | scFv-CD3ε | Lentiviral vector | T Cell | ||
XS-1122-YF5499 | Anti-TRBC1 TCR-ABR (scFv-CD3ε, XW-899) CAR Plasmid, pCDCAR1 | Mouse | XW-899 | Rat | scFv-CD3ε | Lentiviral vector | T Cell | ||
XS-1122-YF6418 | Anti-TRBC1 (XW-898) h(CD28-CD3ζ) CAR, pAAV | Human | XW-898 | Mouse | scFv-CD28-CD3ζ | Adeno-associated viral (AAV) vector | T Cell | ||
XS-1122-YF6419 | Anti-TRBC1 (XW-899) h(CD28-CD3ζ) CAR, pAAV | Mouse | XW-899 | Rat | scFv-CD28-CD3ζ | Adeno-associated viral (AAV) vector | T Cell | ||
XS-1122-YF7338 | Anti-TRBC1 (XW-898) h(41BB-CD3ζ) CAR, pAAV | Human | XW-898 | Mouse | scFv-41BB-CD3ζ | Adeno-associated viral (AAV) vector | T Cell | ||
XS-1122-YF7339 | Anti-TRBC1 (XW-899) h(41BB-CD3ζ) CAR, pAAV | Mouse | XW-899 | Rat | scFv-41BB-CD3ζ | Adeno-associated viral (AAV) vector | T Cell | ||
XS-1122-YF8258 | Anti-TRBC1 (XW-898) h(CD28-41BB-CD3ζ) CAR, pAAV | Human | XW-898 | Mouse | scFv-CD28-41BB-CD3ζ | Adeno-associated viral (AAV) vector | T Cell | ||
XS-1122-YF8259 | Anti-TRBC1 (XW-899) h(CD28-41BB-CD3ζ) CAR, pAAV | Mouse | XW-899 | Rat | scFv-CD28-41BB-CD3ζ | Adeno-associated viral (AAV) vector | T Cell |
The latest newsletter to introduce the latest breaking information, our site updates, field and other scientific news, important events, and insights from industry leaders
LEARN MORE NEWSLETTERCellRapeutics™ In Vivo Cell Engineering: One-stop in vivo T/B/NK cell and macrophage engineering services covering vectors construction to function verification.
LEARN MORE SOLUTIONSilence™ CAR-T Cell: A novel platform to enhance CAR-T cell immunotherapy by combining RNAi technology to suppress genes that may impede CAR functionality.
LEARN MORE NOVEL TECHNOLOGYCanine CAR-T Therapy Development: From early target discovery, CAR design and construction, cell culture, and transfection, to in vitro and in vivo function validation.
LEARN MORE SOLUTION