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UL28

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Cytomegalovirus (CMV) infection elicits a strong T-cell immune response, which increases further during aging in a process termed "memory inflation." CMV downregulates the expression of HLA-A and HLA-B on the surface of infected cells to limit presentation of viral peptides to T-cells although HLA-C is relatively spared as it also engages with inhibitory killer immunoglobulin receptor receptors and therefore reduces lysis by natural killer cells.
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CAT Product Name Target Species TCR Clone Host Species Epitope Allele Vector Type Inquiry & Datasheet
TCR-YC1271 Human anti-UL28 T cell receptor (FRC1-1), pCDTCR1 HCMV FRC1-1 Human FRCPRRFCF HLA-Cw*0702 Lentiviral vector   Add to Cart   Datasheet
TCR-YC1272 Human anti-UL28 T cell receptor (FRC1-2), pCDTCR1 HCMV FRC1-2 Human FRCPRRFCF HLA-Cw*07:02 Lentiviral vector   Add to Cart   Datasheet
TCR-YC1273 Human anti-UL28 T cell receptor (FRC1-3), pCDTCR1 HCMV FRC1-3 Human FRCPRRFCF HLA-Cw*07:02 Lentiviral vector   Add to Cart   Datasheet
TCR-YC1274 Human anti-UL28 T cell receptor (FRC1-4), pCDTCR1 HCMV FRC1-4 Human FRCPRRFCF HLA-Cw*07:02 Lentiviral vector   Add to Cart   Datasheet
TCR-YC1275 Human anti-UL28 T cell receptor (FRC1-5), pCDTCR1 HCMV FRC1-5 Human FRCPRRFCF HLA-Cw*07:02 Lentiviral vector   Add to Cart   Datasheet
TCR-YC1276 Human anti-UL28 T cell receptor (FRC1-6), pCDTCR1 HCMV FRC1-6 Human FRCPRRFCF HLA-Cw*07:02 Lentiviral vector   Add to Cart   Datasheet
TCR-YC1277 Human anti-UL28 T cell receptor (FRC1-7), pCDTCR1 HCMV FRC1-7 Human FRCPRRFCF HLA-Cw*07:02 Lentiviral vector   Add to Cart   Datasheet
TCR-YC1278 Human anti-UL28 T cell receptor (FRC1-8), pCDTCR1 HCMV FRC1-8 Human FRCPRRFCF HLA-Cw*07:02 Lentiviral vector   Add to Cart   Datasheet
TCR-YC1279 Human anti-UL28 T cell receptor (FRC2-1), pCDTCR1 HCMV FRC2-1 Human FRCPRRFCF HLA-Cw*07:02 Lentiviral vector   Add to Cart   Datasheet
TCR-YC1280 Human anti-UL28 T cell receptor (FRC2-2), pCDTCR1 HCMV FRC2-2 Human FRCPRRFCF HLA-Cw*07:02 Lentiviral vector   Add to Cart   Datasheet
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